2015 Clinical trials update in sickle cell anemia (Q28086979)

9 January 2018

review article

1 reference

title

2015 Clinical trials update in sickle cell anemia (English)

1 reference

9 January 2018

0 references

Natasha Archer

1

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9 January 2018

Frédéric Galacteros

series ordinal

2

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9 January 2018

Carlo Brugnara

series ordinal

3

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9 January 2018

language of work or name

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15 July 2015

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9 January 2018

American Journal of Hematology

published in

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9 January 2018

volume

90

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9 January 2018

issue

10

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9 January 2018

page(s)

934-950

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9 January 2018

Survival among children and adults with sickle cell disease in Belgium: Benefit from hydroxyurea treatment

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Proportion of adults with sickle cell anemia and pain crises receiving hydroxyurea

2 June 2018

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Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.

2 June 2018

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Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

2 June 2018

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Potentially therapeutic levels of anti-sickling globin gene expression following lentivirus-mediated gene transfer in sickle cell disease bone marrow CD34+ cells

2 June 2018

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Sickle cell disease: renal manifestations and mechanisms

2 June 2018

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The delay time in sickle cell disease after 40 years: A paradigm assessed

2 June 2018

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Single-dose intravenous gammaglobulin can stabilize neutrophil Mac-1 activation in sickle cell pain crisis

2 June 2018

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Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease

2 June 2018

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Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications.

2 June 2018

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2 June 2018

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MEK inhibitors, novel anti-adhesive molecules, reduce sickle red blood cell adhesion in vitro and in vivo, and vasoocclusion in vivo

2 June 2018

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Update on the use of hydroxyurea therapy in sickle cell disease

2 June 2018

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Genetic variants at HbF-modifier loci moderate anemia and leukocytosis in sickle cell disease in Tanzania

2 June 2018

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Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members

2 June 2018

1 reference

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Hydroxyurea and growth in young children with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Nonmyeloablative HLA-matched sibling allogeneic hematopoietic stem cell transplantation for severe sickle cell phenotype

2 June 2018

1 reference

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Phase 1 study of the E-selectin inhibitor GMI 1070 in patients with sickle cell anemia

2 June 2018

1 reference

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Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina

2 June 2018

1 reference

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Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel

2 June 2018

1 reference

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Ambulatory quality indicators to prevent infection in sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Randomized controlled trial of sildenafil for preventing recurrent ischemic priapism in sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Not simply misshapen red cells: multimolecular and cellular events in sickle vaso-occlusion

2 June 2018

1 reference

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Effects of o-vanillin on K⁺ transport of red blood cells from patients with sickle cell disease.

2 June 2018

1 reference

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Alterations of the arginine metabolome in sickle cell disease: a growing rationale for arginine therapy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

The prevalence of hypertension and abnormal kidney function in children with sickle cell disease -a cross sectional review

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hydroxyurea is associated with lower prevalence of albuminuria in adults with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

A pilot study of eptifibatide for treatment of acute pain episodes in sickle cell disease.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

β-globin gene transfer to human bone marrow for sickle cell disease.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Genetic modulation of HbF in Brazilians with HbSC disease and sickle cell anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Invasive pneumococcal disease among children with and without sickle cell disease in the United States, 1998 to 2009.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Human bulbar conjunctival hemodynamics in hemoglobin SS and SC disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hydroxyurea treatment decreases glomerular hyperfiltration in children with sickle cell anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Effect of propranolol as antiadhesive therapy in sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Sickle cell pain: a critical reappraisal

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Impact of hydroxyurea on clinical events in the BABY HUG trial

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

An update on iron chelation therapy

2 June 2018

1 reference

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Atorvastatin reduces serum cholesterol and triglycerides with limited improvement in vascular function in adults with sickle cell anemia

2 June 2018

1 reference

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A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hemoglobin sickle cell disease complications: a clinical study of 179 cases

2 June 2018

1 reference

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Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin

2 June 2018

1 reference

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Allogeneic hematopoietic stem cell transplantation for sickle cell disease: the time is now.

2 June 2018

1 reference

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Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Fetal hemoglobin in sickle cell anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway

2 June 2018

1 reference

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Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Pulmonary hypertension and NO in sickle cell

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Pulmonary hypertension and nitric oxide depletion in sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Exercise capacity and haemodynamics in patients with sickle cell disease with pulmonary hypertension treated with bosentan: results of the ASSET studies

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Definitions of the phenotypic manifestations of sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Sickle cell disease and stroke

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Sickle red cell adhesion: many issues and some answers

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Impaired vasodilation by red blood cells in sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Ion transport pathology in the mechanism of sickle cell dehydration

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Distribution of dehydration rates generated by maximal Gardos-channel activation in normal and sickle red blood cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Heparin inhibits the flow adhesion of sickle red blood cells to P-selectin

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Endothelial dysfunction in patients with sickle cell disease is related to selective impairment of shear stress-mediated vasodilation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Oral magnesium pidolate: effects of long-term administration in patients with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Nitric oxide successfully used to treat acute chest syndrome of sickle cell disease in a young adolescent

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Silent cerebral infarcts in sickle cell anemia: a risk factor analysis. The Cooperative Study of Sickle Cell Disease.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Stochastic nature and red cell population distribution of the sickling-induced Ca2+ permeability

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Tucaresol increases oxygen affinity and reduces haemolysis in subjects with sickle cell anaemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Adhesion through L-selectin requires a threshold hydrodynamic shear

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives

2 June 2018

1 reference

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Effects of deoxygenation on active and passive Ca2+ transport and on the cytoplasmic Ca2+ levels of sickle cell anemia red cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Adhesion of sickle cells to vascular endothelium is critically dependent on changes in density and shape of the cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

KCl cotransport activity in light versus dense transferrin receptor-positive sickle reticulocytes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

The biophysics of sickle cell hydroxyurea therapy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Improvement of sickle cell anemia by iron‐limited erythropoiesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

The effects of cyanate in vitro on red blood cell metabolism and function in sickle cell anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hemoglobin S gelation and sickle cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Effect of BW12C on oxygen affinity of haemoglobin in sickle-cell disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Sickle cell hemoglobin polymerization

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Vanillin, a potential agent for the treatment of sickle cell anemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Hematologic and clinical responses in patients with sickle cell anemia after chronic extracorporeal red cell carbamylation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

A double-blind, placebo-controlled phase II study of the efficacy and safety of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease

2 June 2018

1 reference

Intravenous magnesium sulfate for vaso-occlusive episodes in sickle cell disease

21 January 2018

1 reference

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

21 January 2018

1 reference

Genetic modifiers of sickle cell anemia in the BABY HUG cohort: influence on laboratory and clinical phenotypes

21 January 2018

1 reference

Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study

21 January 2018

1 reference

The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial.

21 January 2018

1 reference

Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells.

21 January 2018

1 reference

Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation

21 January 2018

1 reference

Montelukast inhibition of resting and GM-CSF-stimulated eosinophil adhesion to VCAM-1 under flow conditions appears independent of cysLT(1)R antagonism

21 January 2018

1 reference

Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis.

21 January 2018

1 reference

Multiple isoforms of the KC1 cotransporter are expressed in sickle and normal erythroid cells

21 January 2018

1 reference

Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: a phase III randomized, placebo-controlled, double-blind study of the Gardos channel blocker se

21 January 2018

1 reference

In vivo action of Vanillin on delay time determined by magnetic relaxation

21 January 2018

1 reference

Effects of 5-hydroxymethyl-2-furfural on the volume and membrane permeability of red blood cells from patients with sickle cell disease.

21 January 2018

1 reference

A multicenter, double-blind, placebo-controlled trial of the PDE9A inhibitor, PF-04447943, in Alzheimer's disease.

21 January 2018

1 reference

Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of the L-arginine-nitric oxide signaling pathway

21 January 2018

1 reference

Pulmonary hypertension as a risk factor for death in patients with sickle cell disease

21 January 2018

1 reference

A hemodynamic study of pulmonary hypertension in sickle cell disease.

21 January 2018

1 reference

21 January 2018

CRISPR, the disruptor

1 reference

Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea

21 January 2018

1 reference

Increased prevalence of osteonecrosis of the femoral head in children and adolescents with sickle-cell disease.

21 January 2018

1 reference

The natural progression of symptomatic humeral head osteonecrosis in adults with sickle cell disease.

21 January 2018

1 reference

Prevalence and progression of chronic kidney disease in adult patients with sickle cell disease.

21 January 2018

1 reference

Pneumococcal vaccination rates in children with sickle cell disease.

21 January 2018

1 reference

Genetic studies of fetal hemoglobin in the Arab-Indian haplotype sickle cell-β0thalassemia

21 January 2018

1 reference

A Study of Induced Hyponatremia in the Prevention and Treatment of Sickle-Cell Crisis

21 January 2018

1 reference

Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease

21 January 2018

1 reference

Phase I study of magnesium pidolate in combination with hydroxycarbamide for children with sickle cell anaemia

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Effects of poloxamer 188 treatment on sickle cell vaso-occlusive crisis: computer-assisted intravital microscopy study.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

[Prevention of sickle cell crises with multiple phlebotomies].

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5752136

Requirement for therapeutic inhibition of sickle haemoglobin gelation

27 November 2018

1 reference

Modulation of Gardos channel activity by cytokines in sickle erythrocytes

21 January 2018

1 reference

12 December 2020

Deoxygenation-induced cation fluxes in sickle cells: relationship between net potassium efflux and net sodium influx

1 reference

12 December 2020

A collaborative, double-blind randomized study of cetiedil citrate in sickle cell crisis

1 reference

12 December 2020

Reduction of painful vaso-occlusive crisis of sickle cell anaemia by tinzaparin in a double-blind randomized trial

1 reference

12 December 2020

Outcome of patients with hemoglobinopathies given either cord blood or bone marrow transplantation from an HLA-identical sibling

1 reference

12 December 2020

A phase I/II study of polymerized bovine hemoglobin in adult patients with sickle cell disease not in crisis at the time of study

1 reference

12 December 2020

1 reference

12 December 2020

Regulation of erythrocyte cation and water content in sickle cell anemia

1 reference

12 December 2020

Haematopoietic stem cell transplantation for severe sickle cell disease in childhood: a single centre experience of 50 patients

1 reference

12 December 2020

Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group

1 reference

12 December 2020

Endothelial-dependent vasodilation is impaired in children with sickle cell disease

1 reference

12 December 2020

The acute chest syndrome in sickle cell disease: incidence and risk factors. The Cooperative Study of Sickle Cell Disease

1 reference

12 December 2020

Inhaled nitric oxide in sickle cell disease with acute chest syndrome

1 reference

12 December 2020

Excellent results and minimal complications of total hip arthroplasty in sickle cell hemoglobinopathy at mid-term follow-up using cementless prosthetic components

1 reference

12 December 2020

Pulmonary complications of sickle cell disease

1 reference

12 December 2020

Using fludarabine to reduce exposure to alkylating agents in children with sickle cell disease receiving busulfan, cyclophosphamide, and antithymocyte globulin transplant conditioning: results of a dose de-escalation trial

1 reference

12 December 2020

Pain in sickle cell disease. Rates and risk factors

1 reference

12 December 2020

Reduced sickle erythrocyte dehydration in vivo by endothelin-1 receptor antagonists

1 reference

12 December 2020

Dehydration of transferrin receptor-positive sickle reticulocytes during continuous or cyclic deoxygenation: role of KCl cotransport and extracellular calcium

1 reference

12 December 2020

Acid pH induces formation of dense cells in sickle erythrocytes

1 reference

12 December 2020

[French guidelines for the management of adult sickle cell disease: 2015 update]

1 reference

12 December 2020

Identifiers

DOI

10.1002/AJH.24116

1 reference

9 January 2018

OpenCitations bibliographic resource ID

4803378

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

9 January 2018

PubMed ID

26178236

1 reference

9 January 2018