Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia (Q28085029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26310815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia (English)

2 references

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22 February 2020

0 references

2

1 reference

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22 February 2020

Stéphane Terry

4

1 reference

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22 February 2020

7

Salem Chouaib

2 references

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22 February 2020

5

Claudine Kieda

2 references

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22 February 2020

author name string

Muhammad Zaeem Noman

1

2 references

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22 February 2020

Yosra Messai

3

2 references

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22 February 2020

Bassam Janji

6

2 references

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22 February 2020

language of work or name

1 reference

26 August 2015

1 reference

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American Journal of Physiology - Cell Physiology

22 February 2020

published in

2 references

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22 February 2020

volume

309

2 references

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22 February 2020

issue

9

2 references

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22 February 2020

page(s)

C569-79

2 references

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HIF-2α/ITPR1 axis: A new saboteur of NK-mediated lysis

22 February 2020

cites work

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Hydroxylation of HIF-1: oxygen sensing at the molecular level

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Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

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7 April 2017

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

7 April 2017

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

7 April 2017

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Applying the principles of stem-cell biology to cancer

7 April 2017

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E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity.

7 April 2017

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HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer

29 September 2017

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Hypoxia-inducible factor as an angiogenic master switch

29 September 2017

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Synergy of Radiotherapy and a Cancer Vaccine for the Treatment of HPV-Associated Head and Neck Cancer

29 September 2017

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Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1.

29 September 2017

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The autophagy sensor ITPR1 protects renal carcinoma cells from NK-mediated killing

29 September 2017

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Epithelial-to-mesenchymal transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune-modulatory properties in cancer cells.

29 September 2017

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Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

29 September 2017

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Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia

29 September 2017

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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

29 September 2017

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ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy

29 September 2017

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29 September 2017

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Molecular pathways: linking tumor microenvironment to epithelial-mesenchymal transition in metastasis

29 September 2017

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Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression.

29 September 2017

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Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment

29 September 2017

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PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

29 September 2017

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Cancer stem cell characteristics of circulating tumor cells

29 September 2017

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A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells

29 September 2017

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Autophagic degradation of GZMB/granzyme B: a new mechanism of hypoxic tumor cell escape from natural killer cell-mediated lysis

29 September 2017

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Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.

29 September 2017

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Hypoxia-regulated overexpression of soluble VEGFR2 controls angiogenesis and inhibits tumor growth

29 September 2017

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Hypoxia-induced downregulation of miR-30c promotes epithelial-mesenchymal transition in human renal cell carcinoma

29 September 2017

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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

29 September 2017

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Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.

29 September 2017

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PIASy mediates hypoxia-induced SIRT1 transcriptional repression and epithelial-to-mesenchymal transition in ovarian cancer cells

29 September 2017

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Hypoxia stimulates the EMT of gastric cancer cells through autocrine TGFβ signaling

29 September 2017

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Targeting the HIF pathway in inflammation and immunity

29 September 2017

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EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

29 September 2017

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Trojan horse at cellular level for tumor gene therapies

29 September 2017

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Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Nanog signaling in cancer promotes stem-like phenotype and immune evasion

29 September 2017

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Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential

29 September 2017

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Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

29 September 2017

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29 September 2017

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In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment

29 September 2017

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Hypoxia-inducible factors: crosstalk between inflammation and metabolism

29 September 2017

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Hypoxia control to normalize pathologic angiogenesis: potential role for endothelial precursor cells and miRNAs regulation

29 September 2017

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Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

29 September 2017

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Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

29 September 2017

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Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response

29 September 2017

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Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide

29 September 2017

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Hypoxia-dependent inhibition of tumor cell susceptibility to CTL-mediated lysis involves NANOG induction in target cells

29 September 2017

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Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

29 September 2017

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Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.

29 September 2017

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Normalization of the vasculature for treatment of cancer and other diseases

29 September 2017

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HIF induces human embryonic stem cell markers in cancer cells.

29 September 2017

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Targeting HIF1α eliminates cancer stem cells in hematological malignancies.

29 September 2017

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Persistent vascular normalization as an alternative goal of anti-angiogenic cancer therapy

29 September 2017

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Angiogenesis and immunity: a bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy

29 September 2017

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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

29 September 2017

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Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

29 September 2017

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Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

29 September 2017

1 reference

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ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading

29 September 2017

1 reference

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Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.

29 September 2017

1 reference

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Hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients.

29 September 2017

1 reference

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FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects stem cell differentiation status.

29 September 2017

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Hypoxia, Snail and incomplete epithelial-mesenchymal transition in breast cancer

29 September 2017

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The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

29 September 2017

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HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery

29 September 2017

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

29 September 2017

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Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Monitoring serial changes in circulating human breast cancer cells in murine xenograft models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Vasculogenesis, angiogenesis, and arteriogenesis: mechanisms of blood vessel formation and remodeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Hypoxia-inducible factors, stem cells, and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Multiple functions of Notch signaling in self-renewing organs and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Mechanisms and functional significance of tumour-induced dendritic-cell defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Targeting hypoxia at the forefront of anticancer immune responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Epithelial-mesenchymal transition induces an antitumor immune response mediated by NKG2D receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4628936

Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung.

2 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

Prostaglandin E₂ receptor EP2 mediates Snail expression in hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

Divergent effects of hypoxia on dendritic cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

The Notch1/cyclooxygenase-2/Snail/E-cadherin pathway is associated with hypoxia-induced hepatocellular carcinoma cell invasion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00207.2015

Circulating tumor cells in metastatic breast cancer: from prognostic stratification to modification of the staging system?

21 January 2018

1 reference

12 December 2020

[Immunotherapy of cancer: promise and reality]

1 reference

12 December 2020

Mammalian and viral IL-10 enhance C-C chemokine receptor 5 but down-regulate C-C chemokine receptor 7 expression by myeloid dendritic cells: impact on chemotactic responses and in vivo homing ability

1 reference

12 December 2020

IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages

1 reference

12 December 2020

Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas

1 reference

12 December 2020

High levels of HIF-2α highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche

1 reference

12 December 2020

The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy

1 reference

12 December 2020

Efficient Treg depletion induces T-cell infiltration and rejection of large tumors

1 reference

12 December 2020

Hypoxia-induced autophagy: a new player in cancer immunotherapy?

1 reference

12 December 2020

Endothelial Programmed Death-1 Ligand 1 (PD-L1) Regulates CD8 + T-Cell–Mediated Injury in the Heart

1 reference

12 December 2020

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1 reference

12 December 2020

Endothelial expression of PD‐L1 and PD‐L2 down‐regulates CD8+ T cell activation and cytolysis

1 reference

12 December 2020

Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions

1 reference

12 December 2020

Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells

1 reference

12 December 2020

Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo

1 reference

12 December 2020

10.1152/AJPCELL.00207.2015

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26310815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26310815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26310815

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26310815%20AND%20SRC:MED&resulttype=core&format=json