CXCR4 over-expression and survival in cancer: a system review and meta-analysis (Q28084663)

C-X-C motif chemokine receptor 4

main subject

1 reference

15 December 2019

1 reference

8 February 2021

1 reference

Hongli Zhao

1

1 reference

Liyuan Guo

2

1 reference

Hong Zhao

3

1 reference

Jiaxin Zhao

4

1 reference

Hao Weng

5

1 reference

Bin Zhao

6

1 reference

language of work or name

1 reference

10 March 2015

7 references

3 April 2019

31 July 2019

3 August 2019

15 December 2019

28 May 2020

8 February 2021

7 references

3 April 2019

31 July 2019

3 August 2019

15 December 2019

28 May 2020

8 February 2021

6

1 reference

issue

7

1 reference

page(s)

5022-40

1 reference

Creative Commons Attribution 2.5 Generic

copyright license

6 references

3 April 2019

31 July 2019

3 August 2019

15 December 2019

28 May 2020

on focus list of Wikimedia project

8 February 2021

ScienceSource

0 references

cites work

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CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin

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20 March 2017

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

20 March 2017

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Expression of chemokine receptor CXCR4 in nasopharyngeal carcinoma: pattern of expression and correlation with clinical outcome

20 March 2017

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Measuring inconsistency in meta-analyses

20 March 2017

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Operating characteristics of a rank correlation test for publication bias

20 March 2017

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20 March 2017

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29 September 2017

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Practical methods for incorporating summary time-to-event data into meta-analysis

20 March 2017

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CXCL12/SDF1 expression by breast cancers is an independent prognostic marker of disease-free and overall survival

20 March 2017

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Genomic organization and promoter characterization of human CXCR4 gene

20 March 2017

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High CXC chemokine receptor 4 expression is an adverse prognostic factor in patients with clear-cell renal cell carcinoma

20 March 2017

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The prognostic value of CXCR4 in ovarian cancer: a meta-analysis

29 September 2017

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Expression of CXCR4 and breast cancer prognosis: a systematic review and meta-analysis

29 September 2017

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Overexpression of CXCR4 is significantly associated with cisplatin-based chemotherapy resistance and can be a prognostic factor in epithelial ovarian cancer

29 September 2017

1 reference

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CXC chemokine receptor 4 expression, CXC chemokine receptor 4 activation, and wild-type nucleophosmin are independently associated with unfavorable prognosis in patients with acute myeloid leukemia

29 September 2017

1 reference

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Expression and prognostic significance of a comprehensive epithelial-mesenchymal transition gene set in renal cell carcinoma.

29 September 2017

1 reference

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The molecular and clinicopathologic characteristics of bilateral breast cancer

29 September 2017

1 reference

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Upregulated expression of C-X-C chemokine receptor 4 is an independent prognostic predictor for patients with gastric cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 heterogeneous expression in esophageal squamous cell cancer and stronger metastatic potential with CXCR4-positive cancer cells

29 September 2017

1 reference

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Cytokine patterns in patients with cancer: a systematic review.

29 September 2017

1 reference

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The expressions of MIF and CXCR4 protein in tumor microenvironment are adverse prognostic factors in patients with esophageal squamous cell carcinoma.

29 September 2017

1 reference

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Small molecule inhibitors of CXCR4.

29 September 2017

1 reference

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High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Significance of CXCR4, phosphorylated STAT3 and VEGF-A expression in resected non-small cell lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Co-expression of CXCR4 and CD133 proteins is associated with poor prognosis in stage II-III colon cancer patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

A review on CXCR4/CXCL12 axis in oncology: no place to hide.

29 September 2017

1 reference

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The influence of transforming growth factor-α, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Correlation between Chemokine Receptor CXCR4 Expression and Prognostic Factors in Patients with Prostate Cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Correlation effect of EGFR and CXCR4 and CCR7 chemokine receptors in predicting breast cancer metastasis and prognosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The influence of tumor-host interactions in the stromal cell-derived factor-1/CXCR4 ligand/receptor axis in determining metastatic risk in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Nuclear localization of CXCR4 determines prognosis for colorectal cancer patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

New insights on the role of CXCR4 in cancer metastasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

In ovarian cancer the prognostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Expression of chemokine receptor CXCR4 in esophageal squamous cell and adenocarcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Persistent CXCR4 expression after preoperative chemoradiotherapy predicts early recurrence and poor prognosis in esophageal cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Expression of CXCR4 and its down-regulation by IFN-gamma in head and neck squamous cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The clinicopathological significance of the expression of CXCR4 protein in oral squamous cell carcinoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

High chemokine receptor CXCR4 level in triple negative breast cancer specimens predicts poor clinical outcome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study.

2 June 2018

1 reference

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A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

High level of CXCR4 in triple-negative breast cancer specimens associated with a poor clinical outcome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Clinicopathological and prognostic significance of chemokine receptor CXCR4 overexpression in patients with esophageal cancer: a meta-analysis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 is a good survival prognostic indicator in multiple myeloma patients.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Association of CXC chemokine receptor type 4 expression and clinicopathologic features in human vulvar cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Prognostic value of CXCR4 expression in patients with clear cell renal cell carcinoma

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Concomitant overexpression of EGFR and CXCR4 is associated with worse prognosis in a new molecular subtype of non-small cell lung cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Cytoplasmic CXCR4 high-expression exhibits distinct poor clinicopathological characteristics and predicts poor prognosis in triple-negative breast cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The prognostic value of CXCR4 in acute myeloid leukemia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The chemokine receptor CXCR4 as a novel independent prognostic marker for node-positive breast cancer patients.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 overexpression is associated with poor outcome in females diagnosed with stage IV non-small cell lung cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 Expression Predicts Patient Outcome and Recurrence Patterns after Hepatic Resection for Colorectal Liver Metastases

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Prognostic impact of CXCR4 and CXCR7 expression in pancreatic adenocarcinoma

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

The expression of CXCR4 and its relationship with matrix metalloproteinase-9/vascular endothelial growth factor in esophageal squamous cell cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Chemokine receptor CXCR4 overexpression predicts recurrence for hormone receptor-positive, node-negative breast cancer patients.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Stromal CXCR4 and CXCL12 expression is associated with distant recurrence and poor prognosis in rectal cancer after chemoradiotherapy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 expression in early breast cancer and risk of distant recurrence.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Overexpression of CXCR4 in primary tumor of patients with HER-2 negative breast cancer was predictive of a poor disease-free survival: a validation study.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Close correlation between CXCR4 and VEGF expression and their prognostic implications in nasopharyngeal carcinoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Prognostic significance of CXCR-4 expression in oral squamous cell carcinoma

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCL12 and CXCR4 in adenocarcinoma of the lung: association with metastasis and survival.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Elevated chemokine receptor CXCR4 expression in primary tumors following neoadjuvant chemotherapy predicts poor outcomes for patients with locally advanced breast cancer (LABC).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

CXCR4 is a prognostic marker in acute myelogenous leukemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467131

Chemokine receptor CXCR4 expression is correlated with VEGF expression and poor survival in soft-tissue sarcoma

27 November 2018

1 reference

12 December 2020

Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression

1 reference

12 December 2020

CXC chemokine receptor 4 is expressed in uveal malignant melanoma and correlates with the epithelioid-mixed cell type

1 reference

12 December 2020

Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

1 reference

12 December 2020

CXCR4 expression in patients with high-risk locally advanced renal cell carcinoma can independently predict increased risk of disease progression and poor overall survival

1 reference

12 December 2020

Chemokine receptor CXCR4 level in primary tumors independently predicts outcome for patients with locally advanced breast cancer

1 reference

12 December 2020

High expression of CXCR4 and CXCR7 predicts poor survival in gallbladder cancer

1 reference

12 December 2020

Clinical significance of CXCR3 and CXCR4 expression in primary melanoma

1 reference

12 December 2020

Expression of CXCL12 and its receptor CXCR4 in esophageal squamous cell carcinoma

1 reference

12 December 2020

Expression of CXCR4 indicates poor prognosis in patients with clear cell carcinoma of the ovary

1 reference

12 December 2020

Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype

1 reference

12 December 2020

Histomorphologic parameters and CXCR4 mRNA and protein expression in sentinel node melanoma metastasis are correlated to clinical outcome

1 reference

12 December 2020

Intratumoural level of SDF-1 correlates with survival in head and neck squamous cell carcinoma

1 reference

12 December 2020

The expression of CXCL12 and CXCR4 in gastric cancer and their correlation to lymph node metastasis

1 reference

12 December 2020

Expression of the chemokine receptor CXCR4 correlates with a favorable prognosis in patients with adenocarcinoma of the lung

1 reference

12 December 2020

Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer

1 reference

12 December 2020

Tumor-cell homing to lymph nodes and bone marrow and CXCR4 expression in esophageal cancer

1 reference

12 December 2020

Expression of CXCR4 is an independent prognostic factor for overall survival and progression-free survival in patients with myelodysplastic syndrome

1 reference

12 December 2020

Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue

1 reference

12 December 2020

CXCR4 membrane expression in node-negative breast cancer

1 reference

12 December 2020

Low expression of microRNA-126 is associated with poor prognosis in colorectal cancer

1 reference

12 December 2020

Concomitant CXCR4 and CXCR7 Expression Predicts Poor Prognosis in Renal Cancer

1 reference

12 December 2020

Prognostic implications of the nuclear localization of Y-box-binding protein-1 and CXCR4 expression in ovarian cancer: their correlation with activated Akt, LRP/MVP and P-glycoprotein expression

1 reference

12 December 2020

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma

1 reference

12 December 2020

Elevated levels of chemokine receptor CXCR4 in HER-2 negative breast cancer specimens predict recurrence

1 reference

12 December 2020

Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancer

1 reference

12 December 2020

Expression of chemokine receptors in human gastric cancer

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.3217

1 reference

release_6ieuvosanff3hiy26jjxgmknoa

4628496

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6ieuvosanff3hiy26jjxgmknoa

24 November 2022

mapped directly with Wikidata item

4628496

1 reference

1 reference

1 reference