Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery (Q28082877)

Matthew J. Bertin

2

1 reference

Karin Kleigrewe

3

1 reference

Tiago F. Leão

4

1 reference

Lena Gerwick

5

1 reference

language of work or name

1 reference

March 2016

1 reference

Journal of Industrial Microbiology & Biotechnology

published in

1 reference

volume

43

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issue

2-3

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page(s)

313-24

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Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis

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1 reference

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Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways

20 March 2017

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Structural Basis for Binding Specificity between Subclasses of Modular Polyketide Synthase Docking Domains

20 March 2017

1 reference

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Biosynthesis and function of polyacetylenes and allied natural products

20 March 2017

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A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

20 March 2017

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The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

20 March 2017

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Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases

20 March 2017

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Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways

20 March 2017

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Hydrocarbon distribution of algae and bacteria, and microbiological activity in sediments

20 March 2017

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Microbial biosynthesis of alkanes

20 March 2017

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Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria

7 April 2017

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The colibactin warhead crosslinks DNA.

29 September 2017

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Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria.

29 September 2017

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Broad-host-range vector system for synthetic biology and biotechnology in cyanobacteria

29 September 2017

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Molecular networking as a dereplication strategy

29 September 2017

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Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses.

29 September 2017

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High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium

29 September 2017

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Using NMR to identify and characterize natural products

29 September 2017

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Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing

29 September 2017

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Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065021

Viequeamide A, a cytotoxic member of the kulolide superfamily of cyclic depsipeptides from a marine button cyanobacterium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065021

Mass spectral molecular networking of living microbial colonies

29 September 2017

1 reference

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The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065021

Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera.

29 September 2017

1 reference

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Conversion of fatty aldehydes to alka(e)nes and formate by a cyanobacterial aldehyde decarbonylase: cryptic redox by an unusual dimetal oxygenase

29 September 2017

1 reference

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Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect

29 September 2017

1 reference

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The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria

29 September 2017

1 reference

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NMR of natural products at the 'nanomole-scale'.

29 September 2017

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Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula

29 September 2017

1 reference

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Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis

29 September 2017

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Metamorphic enzyme assembly in polyketide diversification

29 September 2017

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New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria

29 September 2017

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Chemical defenses: from compounds to communities

29 September 2017

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Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina

29 September 2017

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Cyanobacterial toxins: risk management for health protection

29 September 2017

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Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

29 September 2017

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Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula

29 September 2017

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Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula

29 September 2017

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Characterization of the mupirocin biosynthesis gene cluster from Pseudomonas fluorescens NCIMB 10586.

29 September 2017

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Isolation, structure determination, and biological activity of Lyngbyabellin A from the marine cyanobacterium lyngbya majuscula

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065021

The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide

29 September 2017

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De novo biosynthesis of terminal alkyne-labeled natural products.

2 June 2018

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antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

2 June 2018

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Bacterial biosynthetic gene clusters encoding the anti-cancer haterumalide class of molecules: biogenesis of the broad spectrum antifungal and anti-oomycete compound, oocydin A.

2 June 2018

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NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

2 June 2018

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Modular synthase-encoding gene involved in α-olefin biosynthesis in Synechococcus sp. strain PCC 7002.

2 June 2018

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Standard operating procedure for calculating genome-to-genome distances based on high-scoring segment pairs

2 June 2018

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Isolation and purification of a new kalimantacin/batumin-related polyketide antibiotic and elucidation of its biosynthesis gene cluster

2 June 2018

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Dereplication and de novo sequencing of nonribosomal peptides

2 June 2018

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Carmabins A and B, new lipopeptides from the Caribbean cyanobacterium Lyngbya majuscula

2 June 2018

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Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS.

2 June 2018

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antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

21 January 2018

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Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

21 January 2018

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Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase

21 January 2018

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Hydrocarbons of blue-green algae: geochemical significance.

21 January 2018

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Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine CyanobacteriumPhormidiumsp.

21 January 2018

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12 December 2020

Biosynthesis of the antibiotic bacillaene, the product of a giant polyketide synthase complex of the trans-AT family

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12 December 2020

Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula

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12 December 2020

Protein Radicals in Enzyme Catalysis

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12 December 2020

Lyngbyabellin B, a toxic and antifungal secondary metabolite from the marine cyanobacterium Lyngbya majuscula

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12 December 2020

Dissecting and exploiting intermodular communication in polyketide synthases

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12 December 2020