Systems biology of polycystic kidney disease: a critical review (Q28081359)

polycystic kidney disease

main subject

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inferred from title

author name string

Luis Fernando Menezes

series ordinal

1

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Crossref

Gregory G. Germino

series ordinal

2

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Crossref

language of work or name

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2015

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Wiley interdisciplinary reviews. Systems biology and medicine

published in

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volume

7

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issue

1

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page(s)

39-52

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WGCNA: an R package for weighted correlation network analysis

cites work

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Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study

20 March 2017

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Loss of polycystin-1 or polycystin-2 results in dysregulated apolipoprotein expression in murine tissues via alterations in nuclear hormone receptors

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Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

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PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

20 March 2017

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

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Expanding horizons: ciliary proteins reach beyond cilia

7 April 2017

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Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat.

29 September 2017

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Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.

29 September 2017

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Parallel analysis of mRNA and microRNA microarray profiles to explore functional regulatory patterns in polycystic kidney disease: using PKD/Mhm rat model

29 September 2017

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Urine proteome of autosomal dominant polycystic kidney disease patients

29 September 2017

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Network analysis of a Pkd1-mouse model of autosomal dominant polycystic kidney disease identifies HNF4α as a disease modifier.

29 September 2017

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Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signaling

29 September 2017

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The biomarker enriched proteome of autosomal dominant polycystic kidney disease cyst fluid

29 September 2017

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Characterization of the renal cyst fluid proteome in autosomal dominant polycystic kidney disease (ADPKD) patients

29 September 2017

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Polycystic kidney disease, cilia, and planar polarity.

29 September 2017

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The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation

29 September 2017

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Diagnosis and screening of autosomal dominant polycystic kidney disease

29 September 2017

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Molecular advances in autosomal dominant polycystic kidney disease

29 September 2017

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A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease

29 September 2017

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Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks

29 September 2017

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Characterization of PKD protein-positive exosome-like vesicles

29 September 2017

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Gene expression in early and progression phases of autosomal dominant polycystic kidney disease

29 September 2017

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Periostin induces proliferation of human autosomal dominant polycystic kidney cells through alphaV-integrin receptor

29 September 2017

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Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling

29 September 2017

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A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

29 September 2017

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29 September 2017

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New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies

29 September 2017

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Beta4 integrin and laminin 5 are aberrantly expressed in polycystic kidney disease: role in increased cell adhesion and migration

29 September 2017

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The polycystic kidney disease 1 gene product modulates Wnt signaling

29 September 2017

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Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease

29 September 2017

1 reference

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Protein composition of liver cyst fluid from the BALB/c-cpk/+ mouse model of autosomal recessive polycystic kidney disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

2 June 2018

1 reference

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The robustness and evolvability of transcription factor binding sites.

2 June 2018

1 reference

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Scientific method: statistical errors

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

Validation of gene regulatory networks: scientific and inferential.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

Identification of a unique urinary biomarker profile in patients with autosomal dominant polycystic kidney disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

Gene profiling of polycystic kidneys.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339620

cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway

27 November 2018

1 reference

12 December 2020

Popper, laws, and the exclusion of biology from genuine science

1 reference

12 December 2020

Transcriptome analysis of a rat PKD model: Importance of genes involved in extracellular matrix metabolism

1 reference

12 December 2020

Somatic PKD2 mutations in individual kidney and liver cysts support a "two-hit" model of cystogenesis in type 2 autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Effects of specific genes activating RAGE on polycystic kidney disease

1 reference

12 December 2020

Identification of phosphoproteins in kidney tissues from patients with autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model

1 reference

12 December 2020

Polycystic kidney disease: Polycystin-1 and polycystin-2--it's complicated

1 reference

12 December 2020

Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease

1 reference

12 December 2020