Epigenetic Editing: On the Verge of Reprogramming Gene Expression at Will (Q28080188)

Marianne G. Rots

series ordinal

2

1 reference

language of work or name

1 reference

2016

1 reference

Current genetic medicine reports

published in

1 reference

volume

4

1 reference

issue

4

1 reference

page(s)

170-179

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Creative Commons Attribution 4.0 International

copyright license

start time

1 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s40142-016-0104-3

0 references

cites work

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The language of covalent histone modifications

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KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading

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Integrative analysis of 111 reference human epigenomes

20 March 2017

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

7 April 2017

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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

7 April 2017

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Stability and flexibility of epigenetic gene regulation in mammalian development

7 April 2017

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Charting histone modifications and the functional organization of mammalian genomes

7 April 2017

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A CRISPR-based approach for targeted DNA demethylation

7 April 2017

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CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter.

29 September 2017

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Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation.

29 September 2017

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Repurposing the CRISPR-Cas9 system for targeted DNA methylation

29 September 2017

1 reference

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Dynamics of epigenetic regulation at the single-cell level

29 September 2017

1 reference

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Editing the epigenome: technologies for programmable transcription and epigenetic modulation

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenome Editing: State of the Art, Concepts, and Perspectives

29 September 2017

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Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Highly efficient Cas9-mediated transcriptional programming

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

The Krüppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes by mediating different chromatin states

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

New approaches to manipulating the epigenome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

A protein-tagging system for signal amplification in gene expression and fluorescence imaging

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Locus-specific editing of histone modifications at endogenous enhancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Towards sustained silencing of HER2/neu in cancer by epigenetic editing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Robust, synergistic regulation of human gene expression using TALE activators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

The adjustable nucleosome: an epigenetic signaling module

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenetic modifications as therapeutic targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Chromatin structure and the inheritance of epigenetic information

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenetics, DNA methylation, and chromatin modifying drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Engineering zinc finger protein transcription factors to downregulate the epithelial glycoprotein-2 promoter as a novel anti-cancer treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Histone modifications: signalling receptors and potential elements of a heritable epigenetic code

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Controlling the double helix

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Epigenetic drugs: from chemistry via biology to medicine and back

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Brave new epigenomes: the dawn of epigenetic engineering

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Specific transcriptional enhancement of inducible nitric oxide synthase by targeted promoter demethylation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Induction of angiogenesis in a mouse model using engineered transcription factors

2 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

2 June 2018

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Reduced binding of TFIID to transcriptionally compromised mutants of VP16.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119838

Histone modification: cause or cog?

2 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Engineering of the epigenome: synthetic biology to define functional causality and develop innovative therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

CRISPRs and epigenome editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Epigenome editing made easy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

First CRISPR clinical trial gets green light from US panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Modularized CRISPR/dCas9 effector toolkit for target-specific gene regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Correction of aberrant imprinting by allele-specific epigenome editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40142-016-0104-3

Programmable and highly resolved in vitro detection of 5-methylcytosine by TALEs

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27933223

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S40142-016-0104-3

1 reference

Dimensions Publication ID

3184932

1001333467

0 references

3184932

1 reference

1 reference

1 reference