The Telomerase-Derived Anticancer Peptide Vaccine GV1001 as an Extracellular Heat Shock Protein-Mediated Cell-Penetrating Peptide (Q28076133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Hong Kim

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Seung-Hyun Lee

series ordinal

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bum-Joon Kim

series ordinal

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Molecular Sciences

7 June 2020

language of work or name

1 reference

7 December 2016

10 references

20 June 2019

3 August 2019

28 September 2019

20 November 2019

28 November 2019

19 December 2019

20 December 2019

24 January 2021

31 July 2022

11 references

20 June 2019

3 August 2019

28 September 2019

20 November 2019

28 November 2019

19 December 2019

20 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

24 January 2021

31 July 2022

17

2 references

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7 June 2020

issue

12

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

7 June 2020

copyright license

9 references

20 June 2019

3 August 2019

28 September 2019

20 November 2019

28 November 2019

19 December 2019

20 December 2019

24 January 2021

31 July 2022

0 references

Mechanisms of cellular uptake of cell-penetrating peptides

1 reference

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Hsp70 chaperones: cellular functions and molecular mechanism

20 March 2017

1 reference

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Extracellular HSPs: The Complicated Roles of Extracellular HSPs in Immunity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionally

20 March 2017

1 reference

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DNA vaccines: immunology, application, and optimization*

20 March 2017

1 reference

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Recent advances with liposomes as pharmaceutical carriers

20 March 2017

1 reference

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Molecular chaperones and protein quality control

7 April 2017

1 reference

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Cellular uptake of the tat protein from human immunodeficiency virus

7 April 2017

1 reference

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Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner

7 April 2017

1 reference

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A telomerase-derived peptide regulates reactive oxygen species and hepatitis C virus RNA replication in HCV-infected cells via heat shock protein 90.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

The Anti-inflammatory Effect of GV1001 Mediated by the Downregulation of ENO1-induced Pro-inflammatory Cytokine Production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

The membrane-lytic peptides K8L9 and melittin enter cancer cells via receptor endocytosis following subcytotoxic exposure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Tumor imaging and targeting potential of an Hsp70-derived 14-mer peptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Cell-penetrating peptides as delivery enhancers for vaccine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Cell penetrating peptides and the mechanisms for intracellular entry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Tumor-suppressive effect of a telomerase-derived peptide by inhibiting hypoxia-induced HIF-1α-VEGF signaling axis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Receptor-mediated endocytosis and brain delivery of therapeutic biologics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Heat shock protein-mediated cell penetration and cytosolic delivery of macromolecules by a telomerase-derived peptide vaccine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Cell-penetrating peptides: 20 years later, where do we stand?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Curb challenges of the "Trojan Horse" approach: smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Protein transduction domain delivery of therapeutic macromolecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Improvement of different vaccine delivery systems for cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Current status of GV1001 and other telomerase vaccination strategies in the treatment of cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Heat stress cognate 70 host protein as a potential drug target against drug resistance in hepatitis B virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Peptide-mediated protein delivery-which pathways are penetrable?

29 September 2017

1 reference

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Arginine-rich cell-penetrating peptides.

29 September 2017

1 reference

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Cell-penetrating peptides: application in vaccine delivery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

29 September 2017

1 reference

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Peptides in DNA delivery: current insights and future directions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Telomerase and cancer therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

GV-1001, an injectable telomerase peptide vaccine for the treatment of solid cancers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187854

Cell surface receptors for molecular chaperones.

29 September 2017

1 reference

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TAT transduction: the molecular mechanism and therapeutic prospects

29 September 2017

1 reference

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Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

29 September 2017

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Biodegradable nanoparticles for cytosolic delivery of therapeutics

29 September 2017

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A role for molecular chaperone Hsc70 in reovirus outer capsid disassembly

29 September 2017

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The peptide-binding and ATPase domains of recombinant hsc70 are required to interact with rotavirus and reduce its infectivity.

29 September 2017

1 reference

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Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

29 September 2017

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Cell-penetrating peptides: mechanism and kinetics of cargo delivery

29 September 2017

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Multistep entry of rotavirus into cells: a Versaillesque dance

29 September 2017

1 reference

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Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins

29 September 2017

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Gene silencing in mammals by small interfering RNAs

29 September 2017

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Antigen presentation to CD8+ T cells: cross-priming in infectious diseases.

29 September 2017

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Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo

29 September 2017

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Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial.

2 June 2018

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Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.

21 January 2018

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The effects of gemcitabine and capecitabine combination chemotherapy and of low-dose adjuvant GM-CSF on the levels of myeloid-derived suppressor cells in patients with advanced pancreatic cancer.

21 January 2018

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Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial.

21 January 2018

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Vaccination of patients with cutaneous melanoma with telomerase-specific peptides.

21 January 2018

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Protective effect of peptide GV1001 against renal ischemia-reperfusion injury in mice.

21 January 2018

1 reference

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Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer

21 January 2018

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RNAi-mediated gene silencing in non-human primates.

21 January 2018

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A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27941629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA vaccines: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/27941629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS17122054

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27941629%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

2 references