Biotin (Q28026625)

Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus

Europe PubMed Central

title

Biotin (English)

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ChEBI release 2020-05-28

Janos Zempleni

1

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Subhashinee S K Wijeratne

series ordinal

2

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Yousef I Hassan

series ordinal

3

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language of work or name

English

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publication date

2009

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35

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issue

1

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page(s)

36-46

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cites work

1 reference

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Molecular characterisation and neuropsychological outcome of 21 patients with profound biotinidase deficiency detected by newborn screening and family studies

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Lymphocyte propionyl-CoA carboxylase and its activation by biotin are sensitive indicators of marginal biotin deficiency in humans

20 March 2017

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Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency

20 March 2017

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Multiple biotin-dependent carboxylase deficiencies associated with defects in T-cell and B-cell immunity

20 March 2017

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Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat

20 March 2017

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Human biotinidase isn't just for recycling biotin

20 March 2017

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20 March 2017

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Biotinidase deficiency: the enzymatic defect in late-onset multiple carboxylase deficiency

20 March 2017

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Histone and chromatin cross-talk

20 March 2017

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Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster

7 April 2017

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Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3.

29 September 2017

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Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patterns

29 September 2017

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K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cells

29 September 2017

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Susceptibility to heat stress and aberrant gene expression patterns in holocarboxylase synthetase-deficient Drosophila melanogaster are caused by decreased biotinylation of histones, not of carboxylases

29 September 2017

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An avidin-based assay for histone debiotinylase activity in human cell nuclei

29 September 2017

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Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo

29 September 2017

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Drosophila melanogaster holocarboxylase synthetase is a chromosomal protein required for normal histone biotinylation, gene transcription patterns, lifespan, and heat tolerance

29 September 2017

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Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: A study of the hSMVT system

29 September 2017

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Intestinal absorption of water-soluble vitamins: an update

29 September 2017

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Biotinylation of K12 in histone H4 decreases in response to DNA double-strand breaks in human JAr choriocarcinoma cells

29 September 2017

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Mutations in the holocarboxylase synthetase gene HLCS.

29 September 2017

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Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase

29 September 2017

1 reference

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K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase

29 September 2017

1 reference

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Uptake, localization, and noncarboxylase roles of biotin

29 September 2017

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Marginal biotin deficiency is teratogenic in mice and perhaps humans: a review of biotin deficiency during human pregnancy and effects of biotin deficiency on gene expression and enzyme activities in mouse dam and fetus

29 September 2017

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Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylases

29 September 2017

1 reference

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Biotin biochemistry and human requirements

29 September 2017

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Paradoxical regulation of biotin utilization in brain and liver and implications for inherited multiple carboxylase deficiency.

29 September 2017

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Smoking accelerates biotin catabolism in women

29 September 2017

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Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins

29 September 2017

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3-Hydroxypropionic acid and methylcitric acid are not reliable indicators of marginal biotin deficiency in humans

29 September 2017

1 reference

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Marginal biotin deficiency is teratogenic in ICR mice

29 September 2017

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Transport of biotin in human keratinocytes

29 September 2017

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Indicators of marginal biotin deficiency and repletion in humans: validation of 3-hydroxyisovaleric acid excretion and a leucine challenge

29 September 2017

1 reference

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Lymphocyte propionyl-CoA carboxylase is an early and sensitive indicator of biotin deficiency in rats, but urinary excretion of 3-hydroxypropionic acid is not

29 September 2017

1 reference

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Holocarboxylase synthetase is an obligate participant in biotin-mediated regulation of its own expression and of biotin-dependent carboxylases mRNA levels in human cells.

29 September 2017

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Marginal biotin deficiency during normal pregnancy

29 September 2017

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Marginal biotin deficiency is teratogenic

29 September 2017

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Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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Conflicting indicators of biotin status from a cross-sectional study of normal pregnancy

2 June 2018

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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

21 January 2018

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Jurkat cells respond to biotin deficiency with increased nuclear translocation of NF-kappaB, mediating cell survival

27 November 2018

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27 November 2018

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Biotin is endogenously expressed in select regions of the rat central nervous system

27 November 2018

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Identification of alternatively spliced human biotinidase mRNAs and putative localization of endogenous biotinidase

27 November 2018

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Biotin supply affects rates of cell proliferation, biotinylation of carboxylases and histones, and expression of the gene encoding the sodium-dependent multivitamin transporter in JAr choriocarcinoma cells

27 November 2018

1 reference

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Functional analysis of MCCA and MCCB mutations causing methylcrotonylglycinuria.

27 November 2018

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Monocarboxylate transporter 1 mediates biotin uptake in human peripheral blood mononuclear cells.

27 November 2018

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Biotinidase catalyzes debiotinylation of histones

27 November 2018

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Biotinylation of histones in human cells. Effects of cell proliferation

27 November 2018

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Transport of the biotin dietary derivative biocytin (N-biotinyl-L-lysine) in rat small intestine

27 November 2018

1 reference

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Depletion and repletion of biotinyl enzymes in liver of biotin-deficient rats: evidence of a biotin storage system.

27 November 2018

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Biotin accounts for only half of the total avidin-binding substances in human serum.

27 November 2018

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27 November 2018

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Liver glucokinase of the biotin deficient rat.

27 November 2018

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Biotin supply affects expression of biotin transporters, biotinylation of carboxylases and metabolism of interleukin-2 in Jurkat cells

27 November 2018

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12 December 2020

Biotin deficiency blocks thymocyte maturation, accelerates thymus involution, and decreases nose-rump length in mice

1 reference

12 December 2020

Biliary excretion of biotin and biotin metabolites is quantitatively minor in rats and pigs

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12 December 2020

Cellular Antibody Synthesis in Thiamin, Riboflavin, Biotin and Folic Acid-Deficient Rats

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12 December 2020

A carrier-mediated system for transport of biotin in rat intestine in vitro

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12 December 2020

Biotin absorption by distal rat intestine

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12 December 2020

Microsomal oxidation of alpha-thiocarboxylic acids to sulfoxides

1 reference

12 December 2020

Effects of biotin deficiency on serum fatty acid composition: evidence for abnormalities in humans

1 reference

12 December 2020

Concentrations of biotin metabolites in human milk

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12 December 2020

Intestinal absorption of biotin in the rat

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12 December 2020

Metabolism of Carbonyl-labeled 14C-Biotin in the Rat

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12 December 2020

Regulation of intestinal biotin transport in the rat: effect of biotin deficiency and supplementation

1 reference

12 December 2020

Lymphocyte propionyl-CoA carboxylase and accumulation of odd-chain fatty acid in plasma and erythrocytes are useful indicators of marginal biotin deficiency small star, filled

1 reference

12 December 2020

BIOTIN TRANSPORT BY SMALL INTESTINE OF RAT, HAMSTER, AND OTHER SPECIES

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12 December 2020

Biotinidase deficiency

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12 December 2020

Propionic acidemia: identification of twenty-four novel mutations in Europe and North America

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12 December 2020

A carrier-mediated, Na+ gradient-dependent transport for biotin in human intestinal brush-border membrane vesicles.

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12 December 2020

Indicators of biotin status: a study of patients on prolonged total parenteral nutrition

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12 December 2020

Requirement for biotin and the function of biotin in cells in culture

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12 December 2020