Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity (Q27936364)

ATP-dependent RNA helicase SUB2 YDL084W

GOA release 2020-03-11

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GOA release 2020-03-11

Sonia Jimeno

5

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María L García-Rubio

María García-Rubio

1

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Pablo Huertas

Pablo Huertas

3

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Sebastián Chávez

Sebastián Chávez

2

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Andrés Aguilera

Andrés Aguilera

7

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author name string

Cristina Tous

4

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Rosa Luna

Molecular Genetics and Genomics

6

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language of work or name

English

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publication date

February 2008

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published in

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1 December 2016

279

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issue

2

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page(s)

123-32

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exact match

https://scigraph.springernature.com/pub.10.1007/s00438-007-0301-6

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cites work

HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene.

1 reference

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A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00438-007-0301-6

Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination

21 January 2018

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Hpr1 is preferentially required for transcription of either long or G+C-rich DNA sequences in Saccharomyces cerevisiae.

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Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster

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A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.

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Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex

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A simple in vivo assay for measuring the efficiency of gene length-dependent processes in yeast mRNA biogenesis

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Exploring functional relationships between components of the gene expression machinery.

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Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism

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Interdependence between Transcription and mRNP Processing and Export, and Its Impact on Genetic Stability

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12 December 2020

Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo

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12 December 2020

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

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A set of vectors with a tetracycline-regulatable promoter system for modulated gene expression in Saccharomyces cerevisiae

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Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation

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mRNA export: an assembly line from genes to nuclear pores

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Increase in incidence of chromosome instability and non-conservative recombination between repeats in Saccharomyces cerevisiae hpr1? strains

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Thoc1/Hpr1/p84 is essential for early embryonic development in the mouse

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TREX is a conserved complex coupling transcription with messenger RNA export

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Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.

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12 December 2020

Cotranscriptional mRNP assembly: from the DNA to the nuclear pore

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12 December 2020

Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae

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Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.

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12 December 2020

The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability

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12 December 2020

High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability

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12 December 2020

The connection between transcription and genomic instability

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12 December 2020

Genes with internal repeats require the THO complex for transcription

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12 December 2020

Transitions in RNA polymerase II elongation complexes at the 3' ends of genes

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12 December 2020

A new connection of mRNP biogenesis and export with transcription-coupled repair

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12 December 2020

Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae

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12 December 2020

Molecular evidence for a positive role of Spt4 in transcription elongation

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12 December 2020

An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.

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12 December 2020

Recombination between DNA repeats in yeast hpr1delta cells is linked to transcription elongation

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12 December 2020

The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores

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12 December 2020

Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p

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12 December 2020

Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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12 December 2020