Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair (Q27933147)

Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1

GOA release 2020-03-11

author name string

James M Daley

series ordinal

1

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Thomas E Wilson

series ordinal

2

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Dindial Ramotar

series ordinal

3

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language of work or name

English

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publication date

4 June 2010

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1 reference

1 December 2016

9

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issue

6

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page(s)

690-9

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cites work

1 reference

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Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin

20 March 2017

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Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

20 March 2017

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Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

20 March 2017

1 reference

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Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends

20 March 2017

1 reference

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Actions of aprataxin in multiple DNA repair pathways

20 March 2017

1 reference

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The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

20 March 2017

1 reference

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

20 March 2017

1 reference

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The FHA domain of aprataxin interacts with the C-terminal region of XRCC1

20 March 2017

1 reference

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The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Processing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1.

20 March 2017

1 reference

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Aprataxin, a novel protein that protects against genotoxic stress

20 March 2017

1 reference

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Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatases

20 March 2017

1 reference

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Uncoupling of 3'-phosphatase and 5'-kinase functions in budding yeast. Characterization of Saccharomyces cerevisiae DNA 3'-phosphatase (TPP1).

20 March 2017

1 reference

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Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease

20 March 2017

1 reference

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Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3'-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Molecular views of recombination proteins and their control

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

20 March 2017

1 reference

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Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance

7 April 2017

1 reference

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A subgroup of spinocerebellar ataxias defective in DNA damage responses

29 September 2017

1 reference

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DNA ligases: structure, reaction mechanism, and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Rejoining of DNA double-strand breaks as a function of overhang length

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis

29 September 2017

1 reference

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A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

DNA strand annealing is promoted by the yeast Rad52 protein

29 September 2017

1 reference

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Characterization of a UV endonuclease gene from the fission yeast Schizosaccharomyces pombe and its bacterial homolog

29 September 2017

1 reference

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A new ATP-independent DNA endonuclease from Schizosaccharomyces pombe that recognizes cyclobutane pyrimidine dimers and 6-4 photoproducts

29 September 2017

1 reference

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Sites and structure of gamma radiation-induced DNA strand breaks

29 September 2017

1 reference

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Lambda YES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations

29 September 2017

1 reference

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Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation

29 September 2017

1 reference

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Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin

29 September 2017

1 reference

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Evidence that base stacking potential in annealed 3' overhangs determines polymerase utilization in yeast nonhomologous end joining

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

The novel human gene aprataxin is directly involved in DNA single-strand-break repair.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319107

The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions

27 November 2018

1 reference

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Alternative nucleotide incision repair pathway for oxidative DNA damage

27 November 2018

1 reference

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Expression of Saccharomyces cerevisiae MATa and MAT alpha enhances the HO endonuclease-stimulation of chromosomal rearrangements directed by his3 recombinational substrates.

27 November 2018

1 reference

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Involvement of flap endonuclease 1 in base excision DNA repair.

27 November 2018

1 reference

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tert.-butyl hydroperoxide-mediated DNA base damage in cultured mammalian cells.

27 November 2018

1 reference

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Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks

27 November 2018

1 reference

12 December 2020

Strand Breaks and 5′ End-groups in DNA of Irradiated Thymocytes

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12 December 2020

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12 December 2020

A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

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12 December 2020