Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade (Q27853347)

25

Christel Herold-Mende

0 references

Sebastian Schefzyk

12

Sebastian Schefzyk

0 references

Andreas Unterberg

23

Andreas Unterberg

0 references

Andreas Mock

Andreas Mock

2

0 references

Christian Senft

Christian Senft

17

0 references

Felix Sahm

4

Felix Sahm

0 references

David E Reuss

19

David Reuss

0 references

Philipp Beckhove

20

Philipp Beckhove

0 references

Christin Jungk

3

Christine Jungk

0 references

Ralf Ketter

9

Ralf Ketter

0 references

Simon Matthias May

24

Matthias Simon

0 references

Manfred Westphal

21

Manfred Westphal

0 references

Katrin Lamszus

7

Katrin Lamszus

0 references

Rolf Warta

6

Rolf Warta

0 references

Konstantinos Gousias

8

Konstantinos Gousias

0 references

Saskia Roesch

10

Saskia Roesch

0 references

Carmen Rapp

11

Carmen Rapp

0 references

Steffi Urbschat

13

Steffi Urbschat

0 references

Niels Grabe

18

Niels Grabe

0 references

author name string

Melissa Schmidt

1

0 references

Anna Theresa Ull

5

0 references

Bernd Lahrmann

14

0 references

Almuth F Kessler

15

0 references

Mario Löhr

describes a project that uses

16

0 references

language of work or name

English

0 references

publication date

22 March 2016

0 references

published in

Oncotarget

0 references

volume

7

0 references

issue

12

0 references

page(s)

14551-68

0 references

limma

limma

2 references

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/4924735

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

affy

affy package

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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Mitotic Index is an Independent Predictor of Recurrence-Free Survival in Meningioma.

29 September 2017

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A review of epigenetic and gene expression alterations associated with intracranial meningiomas

29 September 2017

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PTTG1 overexpression in adrenocortical cancer is associated with poor survival and represents a potential therapeutic target

29 September 2017

1 reference

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Overexpression of pituitary tumor transforming gene (PTTG) is associated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma

29 September 2017

1 reference

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Phase II study of alisertib, a selective Aurora A kinase inhibitor, in relapsed and refractory aggressive B- and T-cell non-Hodgkin lymphomas

29 September 2017

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Gene expression profiles of metabolic aggressiveness and tumor recurrence in benign meningioma

29 September 2017

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Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Analysis of gene expression profiling in meningioma: deregulated signaling pathways associated with meningioma and EGFL6 overexpression in benign meningioma tissue and serum

29 September 2017

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Chemotherapy: What is its role in meningioma?

29 September 2017

1 reference

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Pediatric phase I trial and pharmacokinetic study of MLN8237, an investigational oral selective small-molecule inhibitor of Aurora kinase A: a Children's Oncology Group Phase I Consortium study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Expression of the PTTG1 oncogene is associated with aggressive clear cell renal cell carcinoma

29 September 2017

1 reference

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DNA microarray analysis identifies CKS2 and LEPR as potential markers of meningioma recurrence

29 September 2017

1 reference

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The molecular genetics and tumor pathogenesis of meningiomas and the future directions of meningioma treatments.

29 September 2017

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Identification of gene markers associated with aggressive meningioma by filtering across multiple sets of gene expression arrays.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Pathological classification and molecular genetics of meningiomas.

29 September 2017

1 reference

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Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone cluster 1 genes as markers of recurrence in meningiomas.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Correlation between ECT2 gene expression and methylation change of ECT2 promoter region in pancreatic cancer

29 September 2017

1 reference

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Increased prevalence of obesity and obesity-related postoperative complications in male meningioma patients.

29 September 2017

1 reference

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Molecular signatures define two main classes of meningiomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Atypical and anaplastic meningiomas: prognostic implications of clinicopathological features

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Histological classification and molecular genetics of meningiomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Intracranial meningiomas: diagnosis and treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Leptin, obesity and cardiovascular disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

The recurrence of intracranial meningiomas after surgical treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Analysis of gene expression in single live neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Prognostic significance of the mitotic index using the mitosis marker anti-phosphohistone H3 in meningiomas.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Deregulation and mislocalization of the cytokinesis regulator ECT2 activate the Rho signaling pathways leading to malignant transformation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Genomic and transcriptome analysis revealing an oncogenic functional module in meningiomas

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Genetic alterations associated with progression and recurrence in meningiomas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Molecular characterization of central neurocytomas: potential markers for tumor typing and progression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Phase I pharmacokinetic/pharmacodynamic study of MLN8237, an investigational, oral, selective aurora a kinase inhibitor, in patients with advanced solid tumors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Significance of Simpson grading system in modern meningioma surgery: integration of the grade with MIB-1 labeling index as a key to predict the recurrence of WHO Grade I meningiomas

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

A study of UbcH10 expression and its association with recurrence of meningiomas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

PTTG overexpression is correlated with angiogenesis in human pituitary adenomas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metallopr

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patients.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Overexpression of pituitary tumor transforming gene 1 in HCC is associated with angiogenesis and poor prognosis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Prognostically useful gene-expression profiles in acute myeloid leukemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Leptin production by the stomach is up-regulated in obese (fa/fa) Zucker rats.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Allelic gain and amplification on the long arm of chromosome 17 in anaplastic meningiomas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Identification of c-myc as a down-stream target for pituitary tumor-transforming gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

"Malignancy" in meningiomas: a clinicopathologic study of 116 patients, with grading implications.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Meningioma grading: an analysis of histologic parameters.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924735

Expression of PTTG (pituitary tumor transforming gene) in esophageal cancer

27 November 2018

1 reference

12 December 2020

Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

1 reference

12 December 2020

Predisposing conditions and risk factors for development of symptomatic meningioma in adults

1 reference

12 December 2020

Microarray gene expression profiling in meningiomas: differential expression according to grade or histopathological subtype

1 reference

12 December 2020

Meningiomas and obesity reconsidered

1 reference

12 December 2020

Prognostic significance of Ki-67/MIB-1 proliferation index in meningiomas

1 reference

12 December 2020

Allelic losses at 1p, 9q, 10q, 14q, and 22q in the progression of aggressive meningiomas and undifferentiated meningeal sarcomas

1 reference

12 December 2020

Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression

1 reference

12 December 2020

Characterization of pituitary tumor transforming gene in meningiomas

1 reference

12 December 2020

release_cnytryitmjh4lkcymklswg7qsm

Identifiers

DOI

10.18632/ONCOTARGET.7396

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cnytryitmjh4lkcymklswg7qsm

24 November 2022