Epiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis model (Q27853346)

10 January 2018

title

Epiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis model (English)

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10 January 2018

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Alison K Bauer

1

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10 January 2018

Kalpana Velmurugan

2

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10 January 2018

Ka-Na Xiong

3

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10 January 2018

Carla-Maria Alexander

4

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10 January 2018

Julie Xiong

5

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10 January 2018

Rana Brooks

6

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10 January 2018

publication date

19 February 2016

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10 January 2018

published in

Molecular Carcinogenesis

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10 January 2018

volume

56

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10 January 2018

issue

1

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10 January 2018

page(s)

94-105

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10 January 2018

Bronchoalveolar Lavage Fluid Utilized Ex Vivo to Validate In Vivo Findings: Inhibition of Gap Junction Activity in Lung Tumor Promotion is Toll-Like Receptor 4-Dependent

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Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis

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Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells

2 June 2018

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Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

2 June 2018

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Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma

2 June 2018

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2 June 2018

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Genetic mechanisms of susceptibility to oxidative lung injury in mice

2 June 2018

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Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice

2 June 2018

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Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage

2 June 2018

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Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage

2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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Epiregulin is more potent than EGF or TGFalpha in promoting in vitro wound closure due to enhanced ERK/MAPK activation

2 June 2018

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Myeloperoxidase (MPO) genotype and lung cancer histologic types: the MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers

2 June 2018

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The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice

2 June 2018

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

2 June 2018

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Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.

2 June 2018

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2 June 2018

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Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575741

Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575741

Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575741

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2 June 2018

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2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575741

Butylated hydroxytoluene exposure is necessary to induce lung tumors in BALB mice treated with 3-methylcholanthrene.

2 June 2018

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Molecular cloning of mouse epiregulin, a novel epidermal growth factor-related protein, expressed in the early stage of development

2 June 2018

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Epiregulin. A novel epidermal growth factor with mitogenic activity for rat primary hepatocytes

2 June 2018

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Overview of tumor promotion in animals

2 June 2018

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Tumorigenicity of human mesothelial cell line transfected with EJ-ras oncogene

2 June 2018

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Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT).

2 June 2018

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Butylated hydroxytoluene (BHT) induction of pulmonary inflammation: a role in tumor promotion

2 June 2018

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Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature.

21 January 2018

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Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis

21 January 2018

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21 January 2018

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21 January 2018

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Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

21 January 2018

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CCL17 production by dendritic cells is required for NOD1-mediated exacerbation of allergic asthma

21 January 2018

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Multistage carcinogenesis--genetic and epigenetic mechanisms in relation to cancer prevention.

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575741

Macrophage expression of interleukin-10 is a prognostic factor in nonsmall cell lung cancer

27 November 2018

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High-throughput real-time quantitative reverse transcription PCR

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26894620

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Compensatory lung growth after partial pneumonectomy enhances lung tumorigenesis induced by 3-methylcholanthrene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26894620

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amphiregulin and epiregulin expression in neoplastic and inflammatory lesions in the colon

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26894620

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/MC.22475

1 reference

10 January 2018

PMCID

5575741

1 reference

10 January 2018

PubMed ID

26894620

1 reference

10 January 2018