Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen [...] (Q27702205)
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English | Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen [...] |
scientific article |
Statements
Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist (English)
Chris De Savi
Robert H Bradbury
Alfred A Rabow
Richard A Norman
Camila de Almeida
Peter Ballard
David Buttar
Rowena J Callis
Gordon S Currie
Jon O Curwen
Chris D Davies
Craig S Donald
Lyman J L Feron
Helen Gingell
Steven C Glossop
Barry R Hayter
Syeed Hussain
Galith Karoutchi
Scott G Lamont
Philip MacFaul
Thomas A Moss
Stuart E Pearson
Michael Tonge
Graeme E Walker
Hazel M Weir
Zena Wilson
7 October 2015
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