Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration. (Q27691291)

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5 February 2020

review article

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title

Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration (English)

1 reference

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G protein-coupled receptor

5 February 2020

main subject

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author

Dasiel Oscar Borroto Escuela

1

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Diego Guidolin

3

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Kjell Fuxe

6

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5 February 2020

4

Francisco Ciruela

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5 February 2020

Luigi Francesco Agnati

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Luigi F Agnati

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Alexander O Tarakanov

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object named as

Alexander O Tarakanov

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publication date

1 July 2011

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volume

63

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PubMed

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page(s)

463-472

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issue

7

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PubMed

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Enzyme/crystallins: gene sharing as an evolutionary strategy

5 February 2020

cites work

1 reference

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Moonlighting proteins: an intriguing mode of multitasking

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Moonlighting proteins: old proteins learning new tricks.

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Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death

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New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells

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Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP

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Nuclear transport receptor goes moonlighting

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Moonlighting proteins in yeasts

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Evolution and tinkering

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Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

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Receptor-receptor interactions: A novel concept in brain integration

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Allosteric modulation of heterodimeric G-protein-coupled receptors.

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Is the GABA B heterodimer a good drug target?

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Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

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An integrated view on the role of receptor mosaics at perisynaptic level: focus on adenosine A(2A), dopamine D(2), cannabinoid CB(1), and metabotropic glutamate mGlu(5) receptors

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Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors

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Intramembrane receptor-receptor interactions: a novel principle in molecular medicine.

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Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis

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Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders.

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From the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume transmission

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The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions

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Bioinformatics and mathematical modelling in the study of receptor-receptor interactions and receptor oligomerization: focus on adenosine receptors.

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G-protein-coupled receptor heteromer dynamics.

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Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains.

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Triplet puzzle: homologies of receptor heteromers

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Dopamine D2 and D4 receptor heteromerization and its allosteric receptor-receptor interactions

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Functions of heteromeric association between adenosine and P2Y receptors.

21 January 2018

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Neuronal Gq/11-coupled dopamine receptors: an uncharted role for dopamine

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Modulation of D2R-NR2B interactions in response to cocaine

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FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity

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Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases

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The role of intrinsically unstructured proteins in neurodegenerative diseases

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Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal

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D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

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Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology

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On the existence of a possible A2A-D2-β-Arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment.

21 January 2018

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How calmodulin interacts with the adenosine A(2A) and the dopamine D(2) receptors

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Dopamine D2 and 5-hydroxytryptamine 5-HT(₂A) receptors assemble into functionally interacting heteromers.

21 January 2018

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Hetero-dimerization of serotonin 5-HT(2A) and dopamine D(2) receptors

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Heteromeric association creates a P2Y-like adenosine receptor

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The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

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Transactivation joins multiple tracks to the ERK/MAPK cascade

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Fibroblast growth factors in schizophrenia

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Role of neurotrophic factors in depression

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The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior

21 January 2018

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Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models

21 January 2018

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N-methyl-D-aspartate glutamate receptor antagonists and the promise of rapid-acting antidepressants

21 January 2018

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

21 January 2018

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Muscarinic receptor subtypes in neuronal and non-neuronal cholinergic function

21 January 2018

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Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop

21 January 2018

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Muscarinic receptor family interacting proteins: role in receptor function.

21 January 2018

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GPCR interacting proteins (GIP).

21 January 2018

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The M(5) muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization

21 January 2018

1 reference

G protein-coupled receptor oligomerization for what?

21 January 2018

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Debating controversies can enhance creativity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.473

2 references

Consolidated OpenCitations Corpus – April 2017

2745877

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21698749%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

2745877

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2745877