Genetically determined epithelial dysfunction and its consequences for microflora-host interactions (Q27690638)

Niederreiter L

series ordinal

2

1 reference

Blumberg RS

series ordinal

3

1 reference

publication date

November 2011

1 reference

Cellular and Molecular Life Sciences

published in

1 reference

volume

68

1 reference

issue

22

1 reference

page(s)

3643-9

1 reference

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

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1 reference

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Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

20 March 2017

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Homeostasis and inflammation in the intestine

20 March 2017

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

20 March 2017

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

20 March 2017

1 reference

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Reduced Paneth cell alpha-defensins in ileal Crohn's disease

20 March 2017

1 reference

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The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

20 March 2017

1 reference

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

20 March 2017

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

20 March 2017

1 reference

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Autophagy fights disease through cellular self-digestion

20 March 2017

1 reference

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Autophagy in the Pathogenesis of Disease

20 March 2017

1 reference

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Signal integration in the endoplasmic reticulum unfolded protein response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Induction of intestinal Th17 cells by segmented filamentous bacteria

20 March 2017

1 reference

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Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

20 March 2017

1 reference

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Stem cells, self-renewal, and differentiation in the intestinal epithelium

20 March 2017

1 reference

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

The mammalian unfolded protein response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Inflammatory bowel disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Regulation and function of NF-kappaB transcription factors in the immune system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

A microbial symbiosis factor prevents intestinal inflammatory disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system

7 April 2017

1 reference

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Host-bacterial symbiosis in health and disease

7 April 2017

1 reference

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Paneth cells and innate mucosal immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Sensing the outside world: TSLP regulates barrier immunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Enteric defensins are essential regulators of intestinal microbial ecology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

The endoplasmic reticulum stress response in immunity and autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Chronic stimulation of Nod2 mediates tolerance to bacterial products

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Bacterial colonization leads to the colonic secretion of RELMβ/FIZZ2, a novel goblet cell-specific protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-011-0827-Y

Non-apoptotic role of BID in inflammation and innate immunity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

27 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-011-0827-Y

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-011-0827-Y

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984606

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984606

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984606