Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism (Q27681510)

GOA release 2020-03-11

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2 June 2020

Edmund R.S. Kunji

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2 June 2020

author name string

Alex M Hellawell

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2 June 2020

Marilyn Harding

3

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2 June 2020

Paul G Crichton

4

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Airlie J McCoy

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Proceedings of the National Academy of Sciences of the United States of America

2 June 2020

language of work or name

English

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publication date

28 January 2014

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published in

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volume

111

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2 June 2020

page(s)

E426-34

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2 June 2020

issue

4

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Mitochondrial carriers function as monomers.

2 June 2020

cites work

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The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes

20 March 2017

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Characterization of two potentially universal turn motifs that shape the repeated five-residues fold--crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142

20 March 2017

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Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside

20 March 2017

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Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate

20 March 2017

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20 March 2017

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Exchange between extra- and intramitochondrial adenine nucleotides

20 March 2017

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Structure-function studies of adenine nucleotide transport in mitochondria. II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast

20 March 2017

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A third ADP/ATP translocator gene in yeast

20 March 2017

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Ionization constants pKa of cardiolipin

20 March 2017

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The mitochondrial transporter family SLC25: identification, properties and physiopathology

20 March 2017

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Coupling of proton and substrate translocation in the transport cycle of mitochondrial carriers

20 March 2017

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The mechanism of transport by mitochondrial carriers based on analysis of symmetry

20 March 2017

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Diseases caused by defects of mitochondrial carriers: a review

20 March 2017

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Functional and structural role of amino acid residues in the odd-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier

20 March 2017

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Functional and structural role of amino acid residues in the even-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier

20 March 2017

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Bongkrekic acid. An inhibitor of the adenine nucleotide translocase of mitochondria

20 March 2017

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The transmembrane prolines of the mitochondrial ADP/ATP carrier are involved in nucleotide binding and transport and its biogenesis

20 March 2017

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A survey of aspartate-phenylalanine and glutamate-phenylalanine interactions in the protein data bank: searching for anion-π pairs

29 September 2017

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Electrostatic funneling of substrate in mitochondrial inner membrane carriers

29 September 2017

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The ADP and ATP transport in mitochondria and its carrier

29 September 2017

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Mitochondrial carriers in the cytoplasmic state have a common substrate binding site

29 September 2017

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A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA.

29 September 2017

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Projection structure of the atractyloside-inhibited mitochondrial ADP/ATP carrier of Saccharomyces cerevisiae

29 September 2017

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Serine and threonine residues bend alpha-helices in the chi(1) = g(-) conformation.

29 September 2017

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The GxxxG motif: a framework for transmembrane helix-helix association

29 September 2017

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Cardiolipin is not essential for the growth of Saccharomyces cerevisiae on fermentable or non-fermentable carbon sources

29 September 2017

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Positioning hydrogen atoms by optimizing hydrogen-bond networks in protein structures

29 September 2017

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The yeast ADP/ATP carrier. Mutagenesis and second-site revertants

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Structural basis for lipid-mediated interactions between mitochondrial ADP/ATP carrier monomers

2 June 2018

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Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.

2 June 2018

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The alpha-helix dipole and the properties of proteins

2 June 2018

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Position of helical kinks in membrane protein crystal structures and the accuracy of computational prediction

2 June 2018

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Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel

27 November 2018

1 reference

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Structure-function relationships of the C-terminal end of the Saccharomyces cerevisiae ADP/ATP carrier isoform 2.

27 November 2018

1 reference

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The alpha helix dipole: screened out?

27 November 2018

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Chimers of two fused ADP/ATP carrier monomers indicate a single channel for ADP/ATP transport

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910652

Highly conserved charge-pair networks in the mitochondrial carrier family

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910652

Structure-function studies of adenine nucleotide transport in mitochondria. I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria

27 November 2018

1 reference

12 December 2020

Involvement of mitochondria in the assimilatory metabolism of anaerobic Saccharomyces cerevisiae cultures

1 reference

12 December 2020

Functional and structural role of amino acid residues in the matrix alpha-helices, termini and cytosolic loops of the bovine mitochondrial oxoglutarate carrier

1 reference

12 December 2020

Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures

1 reference

12 December 2020

Kinetic, binding and ultrastructural properties of the beef heart adenine nucleotide carrier protein after incorporation into phospholipid vesicles

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12 December 2020

Enhancement of reconstituted ADP,ATP exchange activity by phosphatidylethanolamine and by anionic phospholipids

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12 December 2020

Selection of the nuclear gene for the mitochondrial adenine nucleotide translocator by genetic complementation of the op1 mutation in yeast

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12 December 2020

Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase

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12 December 2020

Intrahelical hydrogen bonding of serine, threonine and cysteine residues within alpha-helices and its relevance to membrane-bound proteins

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12 December 2020

ADP/ATP carrier protein from beef heart mitochondria has high amounts of tightly bound cardiolipin, as revealed by 31P nuclear magnetic resonance

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1320692111

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24474793%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

ADS bibcode

2014PNAS..111E.426R

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2 June 2020

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