Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach (Q27681425)

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1 June 2020

2

Barbara Clough

Barbara

Clough

1 reference

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1 June 2020

8

Andrew R Bottrill

Andrew R

Bottrill

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1 June 2020

10

Malgorzata Broncel

Malgorzata

Broncel

1 reference

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1 June 2020

11

Remigiusz A Serwa

Remigiusz A

Serwa

1 reference

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1 June 2020

14

Robin J Leatherbarrow

Robin J

Leatherbarrow

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15

Rita Tewari

Rita

Tewari

1 reference

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1 June 2020

16

Anthony J Wilkinson

Anthony J

Wilkinson

1 reference

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1 June 2020

17

Anthony A Holder

Anthony A

Holder

1 reference

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1 June 2020

18

Edward W Tate

Edward W

Tate

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1 June 2020

3

Mark D Rackham

Mark D

Rackham

1 reference

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1 June 2020

4

Kaveri Rangachari

Kaveri

Rangachari

1 reference

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1 June 2020

5

James A Brannigan

James A

Brannigan

1 reference

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1 June 2020

6

Munira Grainger

Munira

Grainger

1 reference

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1 June 2020

David K Moss

7

David K

Moss

1 reference

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1 June 2020

William P Heal

series ordinal

9

William P

Heal

1 reference

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Declan Brady

series ordinal

12

Declan

Brady

1 reference

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1 June 2020

David J Mann

series ordinal

13

David J

Mann

1 reference

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full work available at URL

1 June 2020

language of work or name

1 reference

February 2014

0 references

http://eprints.whiterose.ac.uk/121536/

content deliverer

White Rose Research Online

0 references

published in

Nature Chemistry

1 reference

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1 June 2020

volume

6

1 reference

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1 June 2020

page(s)

112-121

1 reference

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1 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24451586%20AND%20SRC:MED&resulttype=core&format=json

Discovery of Novel and Ligand-Efficient Inhibitors of Plasmodium falciparum and Plasmodium vivax N -Myristoyltransferase

1 June 2020

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1 reference

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20 March 2017

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Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

20 March 2017

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Discovery of Plasmodium vivax N -Myristoyltransferase Inhibitors: Screening, Synthesis, and Structural Characterization of their Binding Mode

20 March 2017

1 reference

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Global malaria mortality between 1980 and 2010: a systematic analysis

20 March 2017

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Discovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase Inhibitors

20 March 2017

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N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

20 March 2017

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Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs

20 March 2017

1 reference

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Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite

20 March 2017

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A tetracycline-repressible transactivator system to study essential genes in malaria parasites

20 March 2017

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N-myristoylation of the Rpt2 subunit regulates intracellular localization of the yeast 26S proteasome

20 March 2017

1 reference

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Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites

20 March 2017

1 reference

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Functional dissection of the apicomplexan glideosome molecular architecture

20 March 2017

1 reference

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Myristoylated adenylate kinase-2 of Plasmodium falciparum forms a heterodimer with myristoyltransferase

20 March 2017

1 reference

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Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum

20 March 2017

1 reference

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Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum

20 March 2017

1 reference

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Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs

20 March 2017

1 reference

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Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

20 March 2017

1 reference

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Universal sample preparation method for proteome analysis

7 April 2017

1 reference

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Vivax malaria: neglected and not benign

7 April 2017

1 reference

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Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite

7 April 2017

1 reference

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Subcellular location, phosphorylation and assembly into the motor complex of GAP45 during Plasmodium falciparum schizont development

24 May 2017

1 reference

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Plasmodium falciparum possesses two GRASP proteins that are differentially targeted to the Golgi complex via a higher- and lower-eukaryote-like mechanism

24 May 2017

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Export of Plasmodium falciparum calcium-dependent protein kinase 1 to the parasitophorous vacuole is dependent on three N-terminal membrane anchor motifs

24 May 2017

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Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus

24 May 2017

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N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis

24 May 2017

1 reference

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Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity

29 September 2017

1 reference

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Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target

29 September 2017

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Exploring protein lipidation with chemical biology

29 September 2017

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Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen

29 September 2017

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Functional genetics in Apicomplexa: potentials and limits.

29 September 2017

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Bioorthogonal chemical tagging of protein cholesterylation in living cells

29 September 2017

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Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry

29 September 2017

1 reference

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Protein myristoylation in health and disease

29 September 2017

1 reference

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Imaging the lipidome: omega-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteins

29 September 2017

1 reference

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The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase

29 September 2017

1 reference

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Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species

29 September 2017

1 reference

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Trafficking and signaling by fatty-acylated and prenylated proteins

29 September 2017

1 reference

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A fluorescence-based assay for N-myristoyltransferase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

In-depth analysis of the membrane and cytosolic proteome of red blood cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Characterization of N-myristoyltransferase from Plasmodium falciparum

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

High-throughput profiling of N-myristoylation substrate specificity across species including pathogens.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Getting a chemical handle on proteinpost-translational modification

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Robust fluorescent detection of protein fatty-acylation with chemical reporters.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

N-Myristoyl transferase-mediated protein labelling in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Dual acylation of the 45 kDa gliding-associated protein (GAP45) in Plasmodium falciparum merozoites.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739506

Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites

27 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEM.1830

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCHEM.1830

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24451586%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

0 references

0 references

Dimensions Publication ID

1040949337

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24451586%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24451586%20AND%20SRC:MED&resulttype=core&format=json