A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins (Q27681063)

17

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Thomas E Edwards

object named as

Thomas E Edwards

21

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Ulrike Holzgrabe

object named as

Ulrike Holzgrabe

19

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author name string

Darren W Begley

1

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David Fox

2

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Dominic Jenner

3

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Christina Juli

4

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Phillip G Pierce

5

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Muigai Muruthi

7

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Kris Safford

8

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Vanessa Anderson

9

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Kateri Atkins

10

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Steve R Barnes

11

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Spencer O Moen

12

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Amy C Raymond

13

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Robin Stacy

14

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Peter J Myler

15

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Bart L Staker

16

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Isobel H Norville

18

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Mitali Sarkar-Tyson

20

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Donald D Lorimer

Antimicrobial Agents and Chemotherapy

22

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language of work or name

English

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publication date

2014

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published in

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volume

58

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page(s)

1458-67

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issue

3

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cites work

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The structure of a Burkholderia pseudomallei immunophilin–inhibitor complex reveals new approaches to antimicrobial development

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Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

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20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

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Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides

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FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

20 March 2017

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

20 March 2017

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Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex

20 March 2017

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Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

7 April 2017

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Cyclophilin A and viral infections

7 April 2017

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Cyclophilin A inhibits rotavirus replication by facilitating host IFN-I production

29 September 2017

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New therapies for chronic hepatitis C infection: a systematic review of evidence from clinical trials

29 September 2017

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Classification of scaffold-hopping approaches

29 September 2017

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Gene Composer in a structural genomics environment

29 September 2017

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A Burkholderia pseudomallei macrophage infectivity potentiator-like protein has rapamycin-inhibitable peptidylprolyl isomerase activity and pleiotropic effects on virulence

29 September 2017

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Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein

29 September 2017

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29 September 2017

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Immunophilins: for the love of proteins

29 September 2017

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Solution nuclear magnetic resonance spectroscopy techniques for probing intermolecular interactions

29 September 2017

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Peptidylprolyl cis/trans isomerases (immunophilins): biological diversity--targets--functions

29 September 2017

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Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties.

29 September 2017

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Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays

29 September 2017

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Functional association of cyclophilin A with HIV-1 virions

29 September 2017

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Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells

29 September 2017

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Secretion by Trypanosoma cruzi of a peptidyl-prolyl cis-trans isomerase involved in cell infection

29 September 2017

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Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

29 September 2017

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Immunophilin-sensitive protein phosphatase action in cell signaling pathways

29 September 2017

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Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization

29 September 2017

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Public health assessment of potential biological terrorism agents

29 September 2017

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2 June 2018

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2 June 2018

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Fragment-based drug design: how big is too big?

27 November 2018

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SOFAST-HMQC Experiments for Recording Two-dimensional Deteronuclear Correlation Spectra of Proteins within a Few Seconds

27 November 2018

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Very Fast Two-Dimensional NMR Spectroscopy for Real-Time Investigation of Dynamic Events in Proteins on the Time Scale of Seconds

27 November 2018

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A small molecule suppressor of FK506 that targets the mitochondria and modulates ionic balance in Saccharomyces cerevisiae

27 November 2018

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Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis

27 November 2018

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Relationship of FKBP to PKCI-2

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