E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin (Q27680817)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24316736%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

4

Daniel J St-Cyr

Daniel J

St-Cyr

1 reference

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10 June 2020

8

Manfred Auer

Manfred

Auer

1 reference

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10 June 2020

Hao Huang

1

Hao

Huang

1 reference

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10 June 2020

Stephen Orlicky

3

Stephen

Orlicky

1 reference

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10 June 2020

Amy Ziemba

5

Amy

Ziemba

1 reference

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10 June 2020

Pankaj Garg

6

Pankaj

Garg

1 reference

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10 June 2020

Serge Plamondon

7

Serge

Plamondon

1 reference

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10 June 2020

Sachdev Sidhu

9

Sachdev

Sidhu

1 reference

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10 June 2020

Anne Marinier

10

Anne

Marinier

1 reference

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10 June 2020

Gary Kleiger

11

Gary

Kleiger

1 reference

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10 June 2020

Mike Tyers

12

Mike

Tyers

1 reference

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10 June 2020

Frank Sicheri

13

Frank

Sicheri

1 reference

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10 June 2020

language of work or name

1 reference

February 2014

0 references

published in

Nature Chemical Biology

1 reference

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10 June 2020

volume

10

1 reference

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10 June 2020

issue

2

1 reference

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10 June 2020

page(s)

156-163

1 reference

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describes a project that uses

10 June 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3905752/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A Strategy for Modulation of Enzymes in the Ubiquitin System

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BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

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Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

20 March 2017

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Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface

20 March 2017

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Selective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin Ligase

20 March 2017

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An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme

20 March 2017

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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

20 March 2017

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WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box Proteins

20 March 2017

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Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ

20 March 2017

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Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates

20 March 2017

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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

20 March 2017

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Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

20 March 2017

1 reference

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Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

20 March 2017

1 reference

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Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination

20 March 2017

1 reference

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Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

20 March 2017

1 reference

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Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction

20 March 2017

1 reference

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Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail

20 March 2017

1 reference

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

20 March 2017

2 references

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20 March 2017

https://api.crossref.org/works/10.1038/NCHEMBIO.1412

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

22 April 2017

1 reference

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REFMAC5 for the refinement of macromolecular crystal structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

RING domain E3 ubiquitin ligases

20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Using NMRView to visualize and analyze the NMR spectra of macromolecules

20 March 2017

1 reference

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20 March 2017

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20 March 2017

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E2s: structurally economical and functionally replete

20 March 2017

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Essential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrate

20 March 2017

1 reference

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Building ubiquitin chains: E2 enzymes at work

20 March 2017

1 reference

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

7 April 2017

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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.

7 April 2017

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Design principles of a universal protein degradation machine

29 September 2017

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Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

29 September 2017

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Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions

29 September 2017

1 reference

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Ubiquitin and membrane protein turnover: from cradle to grave

29 September 2017

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Small-molecule stabilization of protein-protein interactions: an underestimated concept in drug discovery?

29 September 2017

1 reference

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Global identification of modular cullin-RING ligase substrates

29 September 2017

1 reference

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Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.

29 September 2017

1 reference

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The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy

29 September 2017

1 reference

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The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

Targeting the ubiquitin system in cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

Sequential backbone assignment of isotopically enriched proteins in D2O by deuterium-decoupled HA(CA)N and HA(CACO)N.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

Stability of thioester intermediates in ubiquitin-like modifications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905752

Association of the disordered C-terminus of CDC34 with a catalytically bound ubiquitin.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1412

The relative rates of thiol-thioester exchange and hydrolysis for alkyl and aryl thioalkanoates in water

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1412

Detection of sequential polyubiquitylation on a millisecond timescale

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1412

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1412

21 January 2018

Identifiers

DOI

10.1038/NCHEMBIO.1412

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24316736%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 June 2020

1029586412

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24316736%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24316736%20AND%20SRC:MED&resulttype=core&format=json