Using protein backbone mutagenesis to dissect the link between ion occupancy and C-type inactivation in K+ channels (Q27680373)

1

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Alexander G Komarov

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Corey A Costantino

3

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Francis I Valiyaveetil

Proceedings of the National Academy of Sciences of the United States of America

4

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language of work or name

English

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publication date

29 October 2013

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published in

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volume

110

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issue

44

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page(s)

17886-91

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cites work

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Structural mechanism of C-type inactivation in K(+) channels

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The Occupancy of Ions in the K+ Selectivity Filter: Charge Balance and Coupling of Ion Binding to a Protein Conformational Change Underlie High Conduction Rates

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Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating

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A gate in the selectivity filter of potassium channels

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Semisynthetic K+ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state

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C-type inactivation of voltage-gated K+ channels: pore constriction or dilation?

29 September 2017

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Structural correlates of selectivity and inactivation in potassium channels

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A multipoint hydrogen-bond network underlying KcsA C-type inactivation

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Structural and functional consequences of an amide-to-ester substitution in the selectivity filter of a potassium channel

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Backbone-Backbone H-Bonds Make Context-Dependent Contributions to Protein Folding Kinetics and Thermodynamics: Lessons from Amide-to-Ester Mutations.

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Molecular determinants of gating at the potassium-channel selectivity filter

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A structural interpretation of voltage-gated potassium channel inactivation.

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29 September 2017

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29 September 2017

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29 September 2017

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Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.

29 September 2017

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Functional consequences of a decreased potassium affinity in a potassium channel pore. Ion interactions and C-type inactivation

29 September 2017

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Contribution of the selectivity filter to inactivation in potassium channels

29 September 2017

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Modulation of C-type inactivation by K+ at the potassium channel selectivity filter

29 September 2017

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pH-dependent gating in the Streptomyces lividans K+ channel

29 September 2017

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29 September 2017

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Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.

29 September 2017

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Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

2 June 2018

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Nobel Lecture. Potassium channels and the atomic basis of selective ion conduction.

2 June 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1314356110

Addition of an alpha-hydroxy acid to the genetic code of bacteria.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1314356110

Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3816462

release_hayyepe3ebg7bdb4hyoe22wesi

27 November 2018

Identifiers

DOI

10.1073/PNAS.1314356110

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ADS bibcode

2013PNAS..11017886M

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hayyepe3ebg7bdb4hyoe22wesi