The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail (Q27678852)

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Language	Label	Description	Also known as
English	The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail	scientific article

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scholarly article

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The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail (English)

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Alexandre R Gingras

object named as

Alexandre R Gingras

1

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author name string

Wilma Puzon-McLaughlin

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Mark H Ginsberg

3

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language of work or name

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publication date

16 August 2013

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Journal of Biological Chemistry

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288

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33

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23639-49

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Structural basis of the junctional anchorage of the cerebral cavernous malformations complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases

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20 March 2017

Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II

1 reference

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20 March 2017

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Deletions in CCM2 are a common cause of cerebral cavernous malformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

KRIT1, a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Three-dimensional structure of the Ras-interacting domain of RalGDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Ras/Rap effector specificity determined by charge reversal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

KRIT1 is mutated in hyperkeratotic cutaneous capillary-venous malformation associated with cerebral capillary malformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

20 March 2017

A mechanism of Rap1-induced stabilization of endothelial cell--cell junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Size-exclusion chromatography can identify faster-associating protein complexes and evaluate design strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Genetics of cavernous angiomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Structural and mechanistic insights into ras association domains of phospholipase C epsilon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Multilocus linkage identifies two new loci for a mendelian form of stroke, cerebral cavernous malformation, at 7p15-13 and 3q25.2-27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

29 September 2017

Gem associates with Ezrin and acts via the Rho-GAP protein Gmip to down-regulate the Rho pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745310

2 June 2018

Ultrastructural pathological features of cerebrovascular malformations: a preliminary report.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.462911

21 January 2018

Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.462911

21 January 2018

heart of glass regulates the concentric growth of the heart in zebrafish.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.462911

21 January 2018

santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.462911

21 January 2018

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.462911

21 January 2018

A gene responsible for cavernous malformations of the brain maps to chromosome 7q

1 reference

https://pubmed.ncbi.nlm.nih.gov/23814056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognizing and defining true Ras binding domains I: biochemical analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23814056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/23814056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.462911

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