A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis (Q27678844)

13

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Olivier Elemento

10

object named as

Olivier Elemento

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Wolfgang Fischle

11

object named as

Wolfgang Fischle

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author name string

Xiao-Jian Sun

1

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Zhanxin Wang

2

0 references

Lan Wang

3

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Yanwen Jiang

4

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Nils Kost

5

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T David Soong

6

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Wei-Yi Chen

7

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Zhanyun Tang

8

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Tomoyoshi Nakadai

9

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Ari Melnick

12

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Stephen D Nimer

14

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Robert G Roeder

Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.

15

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language of work or name

English

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publication date

1 August 2013

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published in

Nature

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volume

500

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issue

7460

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page(s)

93-7

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cites work

1 reference

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Mapping and quantifying mammalian transcriptomes by RNA-Seq

20 March 2017

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The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity

20 March 2017

1 reference

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Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias

20 March 2017

1 reference

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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732535

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

20 March 2017

1 reference

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The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

20 March 2017

1 reference

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The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

20 March 2017

1 reference

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

20 March 2017

1 reference

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ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia

20 March 2017

1 reference

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Homo- and heterodimerization in transcriptional regulation.

29 September 2017

1 reference

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PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

29 September 2017

1 reference

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The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation

29 September 2017

1 reference

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An integrated ChIP-seq analysis platform with customizable workflows

29 September 2017

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Exhaustive search for over-represented DNA sequence motifs with CisFinder

29 September 2017

1 reference

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Mouse models of human AML accurately predict chemotherapy response

29 September 2017

1 reference

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Multivalent binding of the ETO corepressor to E proteins facilitates dual repression controls targeting chromatin and the basal transcription machinery.

29 September 2017

1 reference

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Transforming activity of AML1-ETO is independent of CBFbeta and ETO interaction but requires formation of homo-oligomeric complexes

29 September 2017

1 reference

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AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets

29 September 2017

1 reference

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RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis

29 September 2017

1 reference

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An integrated software system for analyzing ChIP-chip and ChIP-seq data

29 September 2017

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t(8;21)(q22;q22) Fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression

29 September 2017

1 reference

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Choose your partners: dimerization in eukaryotic transcription factors

29 September 2017

1 reference

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A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732535

E protein silencing by the leukemogenic AML1-ETO fusion protein

29 September 2017

1 reference

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The 8;21 translocation in leukemogenesis

29 September 2017

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Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides

29 September 2017

1 reference

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Epigenetic consequences of AML1-ETO action at the human c-FMS locus

29 September 2017

1 reference

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RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

29 September 2017

1 reference

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

29 September 2017

1 reference

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Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

29 September 2017

1 reference

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The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732535

Oncogenic transcription factors in the human acute leukemias

29 September 2017

1 reference

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Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE12287

AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE12287

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE12287

An SCL 3' enhancer targets developing endothelium together with embryonic and adult haematopoietic progenitors.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732535

27 November 2018

Identifiers

DOI

10.1038/NATURE12287

1 reference

Dimensions Publication ID

4787208

1013287002

0 references

4787208

1 reference

1 reference

1 reference