Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase (Q27675612)

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Bing Zhang

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Junpeng Deng

3

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Qingling Tang

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Charulata B Prasannan

5

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Aron W Fenton

MolProbity: all-atom structure validation for macromolecular crystallography

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language of work or name

English

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publication date

22 January 2013

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published in

Biochemistry

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volume

52

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issue

3

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page(s)

466-76

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cites work

1 reference

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20 March 2017

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Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia

20 March 2017

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Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene

20 March 2017

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A deliberate approach to screening for initial crystallization conditions of biological macromolecules

20 March 2017

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

7 April 2017

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A critical evaluation of correlated mutation algorithms and coevolution within allosteric mechanisms

29 September 2017

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Identification of allosteric-activating drug leads for human liver pyruvate kinase

29 September 2017

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Allosteric regulation of human liver pyruvate kinase by peptides that mimic the phosphorylated/dephosphorylated N-terminus

29 September 2017

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Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells

29 September 2017

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p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

29 September 2017

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Glycolytic inhibition by mutation of pyruvate kinase gene increases oxidative stress and causes apoptosis of a pyruvate kinase deficient cell line

29 September 2017

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Possible involvement of pyruvate kinase in acquisition of tolerance to hypoxic stress in glial cells

29 September 2017

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The sulfinic acid switch in proteins

29 September 2017

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Reactive oxygen metabolites and reperfusion injury: aberrant triggering of reticuloendothelial function

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The impact of ions on allosteric functions in human liver pyruvate kinase

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Effector analogues detect varied allosteric roles for conserved protein-effector interactions in pyruvate kinase isozymes

2 June 2018

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The pH dependence of the allosteric response of human liver pyruvate kinase to fructose-1,6-bisphosphate, ATP, and alanine

2 June 2018

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An activating interaction between the unphosphorylated n-terminus of human liver pyruvate kinase and the main body of the protein is interrupted by phosphorylation

2 June 2018

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Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element

2 June 2018

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2 June 2018

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Pyruvate kinase is protected by glutathione-dependent redox balance in human red blood cells exposed to reactive oxygen species

2 June 2018

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The activity and kinetics of pyruvate kinase in hypoxic newborns

27 November 2018

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27 November 2018

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27 November 2018

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Quantitative analysis and interpretation of allosteric behavior

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Mining for allosteric information: natural mutations and positional sequence conservation in pyruvate kinase

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Probing L-pyruvate kinase regulatory phosphorylation site by mutagenesis

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Processing of X-ray diffraction data collected in oscillation mode

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Proteolytic modification of pig and rat liver pyruvate kinase type L including phosphorylatable site

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Distribution of pyruvate kinase type L and M2 in microdissected periportal and perivenous rat liver tissue with different dietary states

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12 December 2020