Solution structure of a tethered Lmo2LIM2/Ldb1LIDcomplex (Q27671803)

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12 February 2020

title

Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex (English)

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12 February 2020

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4

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12 February 2020

Joel P Mackay

5

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12 February 2020

Jacqueline M Matthews

6

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12 February 2020

author name string

Siavoush Dastmalchi

1

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12 February 2020

Lorna Wilkinson-White

2

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12 February 2020

Ann H Kwan

3

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12 February 2020

publication date

25 September 2012

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12 February 2020

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12 February 2020

volume

21

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12 February 2020

issue

11

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12 February 2020

page(s)

1768-1774

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Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification

12 February 2020

cites work

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20 March 2017

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20 March 2017

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The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences

20 March 2017

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Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes

20 March 2017

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Stabilization of a binary protein complex by intein-mediated cyclization

20 March 2017

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Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper

20 March 2017

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Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4

20 March 2017

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A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts

20 March 2017

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The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation

20 March 2017

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The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

20 March 2017

1 reference

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Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development

20 March 2017

1 reference

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Structure of the carboxy-terminal LIM domain from the cysteine rich protein CRP

20 March 2017

1 reference

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

20 March 2017

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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

20 March 2017

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MOLMOL: a program for display and analysis of macromolecular structures

20 March 2017

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Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation

20 March 2017

1 reference

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A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins

20 March 2017

1 reference

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Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins

20 March 2017

1 reference

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Macromolecular NMR spectroscopy for the non-spectroscopist.

20 March 2017

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The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

29 September 2017

1 reference

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It takes two to tango: the structure and function of LIM, RING, PHD and MYND domains.

29 September 2017

1 reference

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The role of LMO2 in development and in T cell leukemia after chromosomal translocation or retroviral insertion

29 September 2017

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A simple method to predict protein flexibility using secondary chemical shifts

29 September 2017

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Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex

29 September 2017

1 reference

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LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins.

29 September 2017

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The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice

29 September 2017

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The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cells

29 September 2017

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The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis.

29 September 2017

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The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

29 September 2017

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Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia

29 September 2017

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The LIM-domain protein Lmo2 is a key regulator of tumour angiogenesis: a new anti-angiogenesis drug target

2 June 2018

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An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions

21 January 2018

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Identification of the key LMO2-binding determinants on Ldb1.

21 January 2018

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1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex.

21 January 2018

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Modular Assembly of RanBP2-Type Zinc Finger Domains to Target Single-Stranded RNA

21 January 2018

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Design, production and characterization of FLIN2 and FLIN4: the engineering of intramolecular ldb1:LMO complexes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22936624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ectopic expression of rhombotin-2 causes selective expansion of CD4-CD8- lymphocytes in the thymus and T-cell tumors in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22936624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/PRO.2153

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12 February 2020

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12 February 2020

PubMed publication ID

22936624

1 reference

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