In Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruzi (Q27664609)

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In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi

Language	Label	Description	Also known as
English	In Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruzi	scientific article	In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi

Statements

scholarly article

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In Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruzi (English)

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infectious disease

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Trypanosoma cruzi

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James H McKerrow

6

object named as

James H McKerrow

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author name string

Yen Ting Chen

1

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Linda S Brinen

2

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Iain D Kerr

3

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Elizabeth Hansell

4

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Patricia S Doyle

5

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William R Roush

7

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language of work or name

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publication date

14 September 2010

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PLoS Neglected Tropical Diseases

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4

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9

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e825

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copyright license

Creative Commons Attribution 4.0 International

14 September 2010

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April 2022 Public Data File from Crossref

copyright status

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Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatB

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Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

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Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

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Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

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29 September 2017

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

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Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain

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The challenge of chagasic cardiomyopathy. The pathologic roles of autonomic abnormalities, autoimmune mechanisms and microvascular changes, and therapeutic implications

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29 September 2017

Structural determinants of specificity in the cysteine protease cruzain

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2 June 2018

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors

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21 January 2018

Vinyl sulfones as mechanism-based cysteine protease inhibitors

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21 January 2018

Synthesis of Peptide Isocyanates and Isothiocyanates

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21 January 2018

Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi

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27 November 2018

Trypanosoma cruzi: biological characterization of 19 clones derived from two chronic chagasic patients. I. Growth kinetics in liquid medium

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27 November 2018

Characterisation of a Trypanosoma cruzi acidic 30 kDa cysteine protease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships for inhibition of papain by peptide Michael acceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20856868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theoretical and practical aspects of proteinase inhibition kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20856868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PNTD.0000825

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