Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4 (Q27662057)

1

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Zucai Suo

3

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Paul Blum

4

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Takehiko Nohmi

5

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Hong Ling

Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase ι

6

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language of work or name

English

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publication date

16 June 2010

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published in

The EMBO Journal

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volume

29

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issue

12

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page(s)

2059-69

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cites work

1 reference

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Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4

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The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

20 March 2017

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Site selectivity of platinum anticancer therapeutics

20 March 2017

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Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta

20 March 2017

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A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment

20 March 2017

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Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole

20 March 2017

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Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion

20 March 2017

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Replication of a cis-syn thymine dimer at atomic resolution

20 March 2017

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Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication

20 March 2017

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Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

20 March 2017

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Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

20 March 2017

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Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

20 March 2017

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Likelihood-enhanced fast translation functions

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

22 April 2017

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Cisplatin: mode of cytotoxic action and molecular basis of resistance

20 March 2017

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Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals

7 April 2017

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Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase

29 September 2017

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What a difference a decade makes: insights into translesion DNA synthesis

29 September 2017

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Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass

29 September 2017

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Molecular mechanisms of resistance and toxicity associated with platinating agents

29 September 2017

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Mechanism of a genetic glissando: structural biology of indel mutations.

29 September 2017

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A role for polymerase eta in the cellular tolerance to cisplatin-induced damage

29 September 2017

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Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis

29 September 2017

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Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?

29 September 2017

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A systematic proteomic study of seed filling in soybean. Establishment of high-resolution two-dimensional reference maps, expression profiles, and an interactive proteome database.

29 September 2017

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Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase

29 September 2017

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Occurrence and characterization of mercury resistance in the hyperthermophilic archaeon Sulfolobus solfataricus by use of gene disruption

29 September 2017

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Targeted disruption of the alpha-amylase gene in the hyperthermophilic archaeon Sulfolobus solfataricus

29 September 2017

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Replication of damaged DNA in mammalian cells: new solutions to an old problem

29 September 2017

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Error-prone repair DNA polymerases in prokaryotes and eukaryotes

29 September 2017

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Specialized DNA polymerases, cellular survival, and the genesis of mutations

29 September 2017

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Cisplatin: from DNA damage to cancer chemotherapy.

29 September 2017

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Extragenic pleiotropic mutations that repress glycosyl hydrolase expression in the hyperthermophilic archaeon Sulfolobus solfataricus.

29 September 2017

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Single d(GpG)/cis-diammineplatinum(II) adduct-induced inhibition of DNA polymerization

29 September 2017

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Molecular characterization of the alpha-glucosidase gene (malA) from the hyperthermophilic archaeon Sulfolobus solfataricus.

29 September 2017

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Roles of DnaK and RpoS in starvation-induced thermotolerance of Escherichia coli

29 September 2017

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DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene

29 September 2017

1 reference

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Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA.

29 September 2017

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Activation of programmed cell death by anticancer agents: cisplatin as a model system

29 September 2017

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X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))]

29 September 2017

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Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II) in murine leukemia L1210 cells.

2 June 2018

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Molecular structure of the complex formed between the anticancer drug cisplatin and d(pGpG): C222(1) crystal form

2 June 2018

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Role of DNA replication in carrier-ligand-specific resistance to platinum compounds in L1210 cells

2 June 2018

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2 June 2018

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Efficiency of extension of mismatched primer termini across from cisplatin and oxaliplatin adducts by human DNA polymerases beta and eta in vitro

2 June 2018

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Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases beta and eta.

21 January 2018

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The low barrier hydrogen bond in enzymatic catalysis.

21 January 2018

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In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic

21 January 2018

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Structure, Recognition, and Processing of Cisplatin-DNA Adducts.

21 January 2018

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Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts.

21 January 2018

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Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability.

21 January 2018

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Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta.

21 January 2018

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The Efficiency and Fidelity of Translesion Synthesis past Cisplatin and Oxaliplatin GpG Adducts by Human DNA Polymerase β

21 January 2018

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