Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism (Q27660209)

9

1 reference

ORCID Public Data File 2021

Yves Bourne

1

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Denis Servent

object named as

Denis Servent

6

1 reference

ORCID Public Data File 2021

author name string

Zoran Radic

2

0 references

Rómulo Aráoz

3

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Todd T Talley

4

0 references

Evelyne Benoit

5

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Palmer Taylor

7

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Jordi Molgó

Proceedings of the National Academy of Sciences of the United States of America

8

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language of work or name

English

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publication date

30 March 2010

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published in

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volume

107

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issue

13

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page(s)

6076-81

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cites work

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

20 March 2017

1 reference

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Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

20 March 2017

1 reference

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Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

20 March 2017

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The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity.

7 April 2017

1 reference

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Spirolide toxin profile of Adriatic Alexandrium ostenfeldii cultures and structure elucidation of 27-hydroxy-13,19-didesmethyl spirolide C.

29 September 2017

1 reference

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Synthesis of macrocyclic shellfish toxins containing spiroimine moieties

29 September 2017

1 reference

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Bivalve molluscs as vectors of marine biotoxins involved in seafood poisoning

29 September 2017

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Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions

29 September 2017

1 reference

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Allosteric mechanisms of signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851920

Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica

29 September 2017

1 reference

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The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851920

Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein

29 September 2017

1 reference

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Neural injury biomarkers of novel shellfish toxins, spirolides: a pilot study using immunochemical and transcriptional analysis.

29 September 2017

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Serine-specific phosphorylation of nicotinic receptor associated 43K protein

2 June 2018

1 reference

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Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851920

Characterization of spirolides a, c, and 13-desmethyl c, new marine toxins isolated from toxic plankton and contaminated shellfish.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912372107

Spirolides isolated from Danish strains of the toxigenic dinoflagellate Alexandrium ostenfeldii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912372107

Acute toxicity of gymnodimine to mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912372107

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912372107

Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912372107

Characterization of cembranoid interaction with the nicotinic acetylcholine receptor.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851920

New analogue of gymnodimine from a Gymnodinium species

27 November 2018

1 reference

12 December 2020

Gymnodimine C, an isomer of gymnodimine B, from Karenia selliformis

1 reference

12 December 2020

Relationship between reversible antagonist occupancy and the functional capacity of the acetylcholine receptor

1 reference

12 December 2020

Lophotoxin is a slow binding irreversible inhibitor of nicotinic acetylcholine receptors

1 reference

12 December 2020

Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha7 nicotinic receptor

1 reference

12 December 2020

Detection and identification of spirolides in norwegian shellfish and plankton

1 reference

12 December 2020

Spirolide composition of micro-extracted pooled cells isolated from natural plankton assemblages and from cultures of the dinoflagellate Alexandrium ostenfeldii

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0912372107

1 reference

3909744

ADS bibcode

2010PNAS..107.6076B

0 references

3909744

1 reference

1 reference

1 reference