Structure of Natural Killer Cell Receptor KLRG1 Bound to E-Cadherin Reveals Basis for MHC-Independent Missing Self Recognition (Q27656461)

1

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Maike Hofmann

2

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Qian Wang

3

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Leslie Teng

4

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Lukasz K Chlewicki

5

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Hanspeter Pircher

Structural basis for NKG2A/CD94 recognition of HLA-E.

6

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language of work or name

English

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publication date

17 July 2009

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published in

Immunity

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volume

31

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page(s)

35-46

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issue

1

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cites work

1 reference

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Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors

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CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

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The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism

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Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

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Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

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Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity

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Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation

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Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors

20 March 2017

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Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b)

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Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin

20 March 2017

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C-cadherin ectodomain structure and implications for cell adhesion mechanisms

20 March 2017

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Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex

20 March 2017

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Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA

20 March 2017

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Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand

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Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin

20 March 2017

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Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors

20 March 2017

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A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation

20 March 2017

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Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors

20 March 2017

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Structural basis of calcium-induced E-cadherin rigidification and dimerization

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E-cadherin gene mutations provide clues to diffuse type gastric carcinomas

20 March 2017

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20 March 2017

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20 March 2017

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The atomic structure of protein-protein recognition sites

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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Shape complementarity at protein/protein interfaces

20 March 2017

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20 March 2017

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Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor

20 March 2017

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20 March 2017

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Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57

20 March 2017

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Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography

20 March 2017

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Regulation of cadherin-mediated adhesion in morphogenesis

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7 April 2017

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Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

7 April 2017

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Interaction of KLRG1 with E-cadherin: new functional and structural insights

29 September 2017

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29 September 2017

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29 September 2017

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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

29 September 2017

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Tumor-associated E-cadherin mutations affect binding to the killer cell lectin-like receptor G1 in humans

29 September 2017

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29 September 2017

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KLRG1 binds cadherins and preferentially associates with SHIP-1.

29 September 2017

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Structural basis for recognition of MHC and MHC-like ligands by natural killer cell receptors

29 September 2017

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Cytolytic responses: cadherins put out the fire

29 September 2017

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29 September 2017

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Cadherins and catenins in breast cancer

29 September 2017

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2B4 (CD244)-CD48 interactions provide a novel MHC class I-independent system for NK-cell self-tolerance in mice

29 September 2017

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2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells

29 September 2017

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Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history

29 September 2017

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29 September 2017

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29 September 2017

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2F1 antigen, the mouse homolog of the rat "mast cell function-associated antigen", is a lectin-like type II transmembrane receptor expressed by natural killer cells

29 September 2017

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Cadherins in cancer: implications for invasion and metastasis

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29 September 2017

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NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules

29 September 2017

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Mutations designed to destabilize the receptor-bound conformation increase MICA-NKG2D association rate and affinity.

2 June 2018

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27 November 2018

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27 November 2018

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27 November 2018

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https://pubmed.ncbi.nlm.nih.gov/19604491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19604491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A monoclonal antibody that inhibits secretion from rat basophilic leukemia cells and binds to a novel membrane component

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19604491

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1016/J.IMMUNI.2009.04.019

1 reference

4209444

4209444

1 reference

1 reference

1 reference