2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice (Q27650349)

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2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice
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    2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice (English)
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    Lars Johansson
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    Christopher Fotsch
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    Michael D Bartberger
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    Victor M Castro
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    Michelle Chen
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    Maurice Emery
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    Sonja Gustafsson
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    Clarence Hale
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    Dean Hickman
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    Evert Homan
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    Steven R Jordan
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    Renee Komorowski
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    Aiwen Li
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    Kenneth McRae
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    George Moniz
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    Guy Matsumoto
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    Carlos Orihuela
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    Gunnar Palm
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    Murielle Veniant
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    Minghan Wang
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    Meredith Williams
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    Jiandong Zhang
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    22 May 2008
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    51
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    10
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    2933-43
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