Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex (Q27644666)

1

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Xiaogang Niu

2

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Yingqi Xu

3

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Jihui Wu

The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain

4

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publication date

June 2007

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published in

Protein Science

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volume

16

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issue

6

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page(s)

1053-62

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cites work

1 reference

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PDZ tandem of human syntenin: crystal structure and functional properties

20 March 2017

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Crystal structure of GRIP1 PDZ6-peptide complex reveals the structural basis for class II PDZ target recognition and PDZ domain-mediated multimerization

20 March 2017

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Novel mode of ligand recognition by the Erbin PDZ domain

20 March 2017

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Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions

20 March 2017

1 reference

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The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif

20 March 2017

1 reference

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Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator

20 March 2017

1 reference

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Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1

20 March 2017

2 references

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20 March 2017

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Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex

20 March 2017

1 reference

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Crystal structure of a PDZ domain

20 March 2017

1 reference

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Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

20 March 2017

1 reference

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Raster3D Version 2.0. A program for photorealistic molecular graphics

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

20 March 2017

1 reference

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MOLMOL: a program for display and analysis of macromolecular structures

20 March 2017

1 reference

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 March 2017

1 reference

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The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data

20 March 2017

1 reference

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Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

20 March 2017

1 reference

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PDZ domains: structural modules for protein complex assembly

20 March 2017

1 reference

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Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

AF6 negatively regulates Rap1-induced cell adhesion

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

The AF-6 Homolog Canoe Acts as a Rap1 Effector During Dorsal Closure of the Drosophila Embryo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

FAST-Modelfree: a program for rapid automated analysis of solution NMR spin-relaxation data

29 September 2017

1 reference

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PDZ Domain Proteins: Plug and Play!

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Signalling to and from tight junctions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Nectin and afadin: novel organizers of intercellular junctions.

29 September 2017

1 reference

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The biology of chronic myeloid leukemia

29 September 2017

1 reference

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An account of NMR in structural biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

AF-6/cno: neither a kinesin nor a myosin, but a bit of both.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Heteronuclear X-filter 1H PFG double-quantum experiments for the proton resonance assignment of a ligand bound to a protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

A novel family of Ras-binding domains.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Classification of PDZ domains

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Absence of the tight junctional protein AF-6 disrupts epithelial cell-cell junctions and cell polarity during mouse development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206671

Solution structure of AF-6 PDZ domain and its interaction with the C-terminal peptides from Neurexin and Bcr

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17473018