ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis (Q27643059)

1

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Bart Staker

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Sridhar G Prasad

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Saurabh Menon

4

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Jin Tang

5

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Thomas Parsons

6

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Dominic Ryan

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Martin Fisher

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David Williams

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Natalie A Dales

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Michael A Patane

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Michael W Pantoliano

Journal of Biological Chemistry

12

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language of work or name

English

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publication date

23 April 2004

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published in

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volume

279

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page(s)

17996-8007

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issue

17

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cites work

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Angiotensin-converting enzyme 2 is an essential regulator of heart function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

The SARS-CoV S glycoprotein: expression and functional characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

The angiotensin-converting enzyme gene family: genomics and pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

The role of ACE2 in cardiovascular physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Crystal structure of the human angiotensin-converting enzyme-lisinopril complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Monoclonal anti-DNA antibodies: structure, specificity, and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

21 January 2018

Prolyl Oligopeptidase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

A giant protease with a twist: the TPP II complex from Drosophila studied by electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Evolutionary families of metallopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Structure of astacin with a transition-state analogue inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Structural mechanisms for domain movements in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

A database of macromolecular motions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Implications of protein flexibility for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

A new class of angiotensin-converting enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Structure of neurolysin reveals a deep channel that limits substrate access

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Angiotensin I-converting enzyme transition state stabilization by HIS1089: evidence for a catalytic mechanism distinct from other gluzincin metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Anion activation of angiotensin converting enzyme: dependence on nature of substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Arg(1098) is critical for the chloride dependence of human angiotensin I-converting enzyme C-domain catalytic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Using CLUSTAL for multiple sequence alignments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Knowledge-based protein secondary structure assignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

A deeply recessed active site in angiotensin-converting enzyme is indicated from the binding characteristics of biotin-spacer-inhibitor reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

New developments in phase refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200

Male–female differences in fertility and blood pressure in ACE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311191200