The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding (Q27641616)

2

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Rina Levy

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Gideon Schreiber

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Jacob Anglister

Identification of pairwise interactions in the alpha-neurotoxin-nicotinic acetylcholine receptor complex through double mutant cycles

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language of work or name

English

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publication date

July 2003

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published in

Structure

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volume

11

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issue

7

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page(s)

791-802

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cites work

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Structural design and molecular evolution of a cytokine receptor superfamily

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Treating cancer with PEG Intron: pharmacokinetic profile and dosing guidelines for an improved interferon-alpha-2b formulation

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The human interferon receptor: NMR-based modeling, mapping of the IFN-alpha 2 binding site, and observed ligand-induced tightening

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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

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Ligand-induced association of the type I interferon receptor components

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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Identification of critical residues in bovine IFNAR-1 responsible for interferon binding

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

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Why do so many cancer patients fail to respond to interferon therapy?

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Amino acid type determination in the sequential assignment procedure of uniformly 13C/15N-enriched proteins.

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Correlation of Backbone Amide and Aliphatic Side-Chain Resonances in 13C/15N-Enriched Proteins by Isotropic Mixing of 13C Magnetization

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Crystal structure of the extracellular region of human tissue factor

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Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site

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The crystal structure of human interferon beta at 2.2-A resolution

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Cancer immunotherapy: the interferon-alpha experience

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The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution

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MOLMOL: a program for display and analysis of macromolecular structures

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Three-dimensional model of a human interferon-alpha consensus sequence

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Shared receptor components but distinct complexes for alpha and beta interferons

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Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: applicati

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The type I interferon receptor: structure, function, and evolution of a family business.

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Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor

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The human interferon alpha/beta receptor: characterization and molecular cloning

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Peginterferon-alpha-2a (40 kD): a review of its use in the management of chronic hepatitis C.

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Interferons and their actions

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New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface

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Biophysical analysis of the interaction of human ifnar2 expressed in E. coli with IFNalpha2.

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Mutational and structural analysis of the binding interface between type I interferons and their receptor Ifnar2

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Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

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Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking

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Systematic mutational mapping of sites on human interferon-beta-1a that are important for receptor binding and functional activity

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7 January 2021

Solution NMR of proteins within polyacrylamide gels: diffusional properties and residual alignment by mechanical stress or embedding of oriented purple membranes

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Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles.

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Rapid, electrostatically assisted association of proteins

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New insights into the mechanism of protein-protein association

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How cells respond to interferons

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Alignment of Biopolymers in Strained Gels: A New Way To Create Detectable Dipole−Dipole Couplings in High-Resolution Biomolecular NMR

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Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA

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Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor

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Human interferon alpha enters cells by receptor-mediated endocytosis

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A model of a gp120 V3 peptide in complex with an HIV-neutralizing antibody based on NMR and mutant cycle-derived constraints

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