Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection (Q27640572)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165110%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection (English)

1 reference

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14 March 2020

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14 March 2020

Neelakshi Gohain

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14 March 2020

Jason S. McLellan

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14 March 2020

Yongjun Guan

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14 March 2020

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Peter D Kwong

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14 March 2020

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Timothy S Luongo

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James E Robinson

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14 March 2020

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Robert K Louder

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14 March 2020

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Yongping Yang

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14 March 2020

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Marie Pancera

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14 March 2020

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Priyamvada Acharya

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14 March 2020

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Loïc Martin

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14 March 2020

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Mohammad M Sajadi

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Anthony L DeVico

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George K Lewis

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14 March 2020

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Roberta Kamin-Lewis

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14 March 2020

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Marzena Pazgier

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14 March 2020

author name string

Xueji Wu

4

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14 March 2020

Lei Yu

5

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14 March 2020

Tongyun Liu

6

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14 March 2020

Wensheng Huang

7

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14 March 2020

Chih-Chin Huang

8

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Young Do Kwon

9

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14 March 2020

Baoshan Zhang

15

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14 March 2020

Robin Flinko

16

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14 March 2020

James S Foulke

17

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14 March 2020

publication date

27 August 2014

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14 March 2020

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14 March 2020

volume

88

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14 March 2020

page(s)

12895-12906

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14 March 2020

issue

21

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

14 March 2020

cites work

1 reference

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

20 March 2017

1 reference

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Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1

20 March 2017

1 reference

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Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

20 March 2017

1 reference

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ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge

20 March 2017

1 reference

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Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

20 March 2017

1 reference

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HIV-specific antibodies capable of ADCC are common in breastmilk and are associated with reduced risk of transmission in women with high viral loads

20 March 2017

1 reference

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Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

20 March 2017

1 reference

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Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

20 March 2017

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

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Molecular architecture of native HIV-1 gp120 trimers

20 March 2017

1 reference

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Inference of macromolecular assemblies from crystalline state

20 March 2017

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Solving structures of protein complexes by molecular replacement with Phaser

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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20 March 2017

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PHENIX: building new software for automated crystallographic structure determination

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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PIC: Protein Interactions Calculator

20 March 2017

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Immune-correlates analysis of an HIV-1 vaccine efficacy trial

20 March 2017

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Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

7 April 2017

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CD4-induced activation in a soluble HIV-1 Env trimer

29 September 2017

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Epitope target structures of Fc-mediated effector function during HIV-1 acquisition

29 September 2017

1 reference

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HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2.

29 September 2017

1 reference

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Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

29 September 2017

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Antigenic properties of the HIV envelope on virions in solution

29 September 2017

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Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.

29 September 2017

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Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk

29 September 2017

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Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques

29 September 2017

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The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.

29 September 2017

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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

29 September 2017

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Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

29 September 2017

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Origin, diversity, and maturation of human antiviral antibodies analyzed by high-throughput sequencing

29 September 2017

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Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding

29 September 2017

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Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes

29 September 2017

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Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac2

29 September 2017

1 reference

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Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

29 September 2017

1 reference

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An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

29 September 2017

1 reference

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Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies

29 September 2017

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Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure

29 September 2017

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Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions

29 September 2017

1 reference

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Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers

29 September 2017

1 reference

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Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines.

29 September 2017

1 reference

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Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques

29 September 2017

1 reference

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CD4-induced epitopes in the HIV envelope glycoprotein, gp120.

29 September 2017

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Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cells

29 September 2017

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Kinetic rates of antibody binding correlate with neutralization sensitivity of variant simian immunodeficiency virus strains

29 September 2017

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Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies

29 September 2017

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Antigenic properties of the human immunodeficiency virus envelope during cell-cell fusion

29 September 2017

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Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro

29 September 2017

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Expression and characterization of a single-chain polypeptide analogue of the human immunodeficiency virus type 1 gp120-CD4 receptor complex

29 September 2017

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Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment

29 September 2017

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Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.

29 September 2017

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Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies

29 September 2017

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Epitope mapping of ibalizumab, a humanized anti-CD4 monoclonal antibody with anti-HIV-1 activity in infected patients

29 September 2017

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Fc receptor but not complement binding is important in antibody protection against HIV.

2 June 2018

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Protein and carbohydrate structural analysis of a recombinant soluble CD4 receptor by mass spectrometry

2 June 2018

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Comprehensive investigation of common antibody-dependent cell-mediated cytotoxicity antibody epitopes of HIV-1 CRF01_AE gp120.

2 June 2018

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Vaccines to antibodies: grow up!

27 November 2018

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Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rate

27 November 2018

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A simplified method for the rapid fluorometric assessment of antibody-dependent cell-mediated cytotoxicity.

27 November 2018

1 reference

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Structural features of HIV envelope defined by antibody escape mutant analysis.

27 November 2018

1 reference

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Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection

27 November 2018

1 reference

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The PDBFINDER database: a summary of PDB, DSSP and HSSP information with added value.

27 November 2018

1 reference

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Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS

27 November 2018

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12 December 2020

Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.02194-14

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165110%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165110%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165110%20AND%20SRC:MED&resulttype=core&format=json