Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site (Q27625712)

1

0 references

J B Schnier

2

0 references

S E Zographos

3

0 references

V T Skamnaki

4

0 references

K E Tsitsanou

5

0 references

L N Johnson

Journal of Biological Chemistry

6

0 references

language of work or name

English

0 references

publication date

3 November 2000

0 references

published in

0 references

volume

275

0 references

issue

44

0 references

page(s)

34566-73

0 references

cites work

Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Chemical inhibitors of cyclin-dependent kinases: insights into design from X-ray crystallographic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Cyclin-dependent kinases: initial approaches to exploit a novel therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

The family of glycogen phosphorylases: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

N-acetyl-beta-D-glucopyranosylamine: a potent T-state inhibitor of glycogen phosphorylase. A comparison with alpha-D-glucose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Allosteric inhibition of glycogen phosphorylaseaby the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarboxylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

A new allosteric site in glycogen phosphorylase b as a target for drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Subunit interactions and their relation to the allosteric properties of rabbit skeletal muscle phosphorylase b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

THE ROLE OF ADENYLIC ACID IN THE ACTIVATION OF PHOSPHORYLASE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Improved Fourier coefficients for maps using phases from partial structures with errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Site-site interactions in glycogen phosphorylase b probed by ligands specific for each site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200

Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004485200