Diverse structural solutions to catalysis in a family of antibodies (Q27620477)

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T Tsumuraya

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I Fujii

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M Knossow

Nature of Forces between Large Molecules of Biological Interest*

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language of work or name

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15 November 1999

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published in

Structure

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volume

7

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issue

11

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page(s)

1385-93

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cites work

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7 January 2021

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7 January 2021

Selective chemical catalysis by an antibody

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7 January 2021

Catalytic antibodies--reaching adolescence?

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7 January 2021

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

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7 January 2021

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7 January 2021

Site-directed mutagenesis of a catalytic antibody: an arginine and a histidine residue play key roles

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7 January 2021

Generation of a catalytic antibody by site-directed mutagenesis

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7 January 2021

Creation of a ribonuclease abzyme through site-directed mutagenesis

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7 January 2021

Phage display of a catalytic antibody to optimize affinity for transition-state analog binding

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7 January 2021

26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity

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7 January 2021

Structure and specificity of the anti-digoxin antibody 40-50

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7 January 2021

Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies

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7 January 2021

Mechanistically different catalytic antibodies obtained from immunization with a single transition-state analog

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7 January 2021

Isoabzymes: structurally and mechanistically similar catalytic antibodies from the same immunization

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7 January 2021

Structural convergence in the active sites of a family of catalytic antibodies

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7 January 2021

A comparison of the crystallographic structures of two catalytic antibodies with esterase activity

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7 January 2021

Correlation between Antigen-Combining-Site Structures and Functions within a Panel of Catalytic Antibodies Generated against a Single Transition State Analog

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7 January 2021

A common ancestry for multiple catalytic antibodies generated against a single transition-state analog.

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7 January 2021

A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1. 8 A resolution.

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7 January 2021

Antibody-antigen interactions: new structures and new conformational changes

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7 January 2021

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7 January 2021

Conformations of the third hypervariable region in the VH domain of immunoglobulins

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7 January 2021

Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody

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7 January 2021

Hydrolytic antibodies: variations on a theme

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7 January 2021

Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization

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7 January 2021

Mechanistic studies of a tyrosine-dependent catalytic antibody

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7 January 2021

Prodrug activation via catalytic antibodies

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7 January 2021

AMoRe: an automated package for molecular replacement

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7 January 2021

Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1

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7 January 2021

The Protein Data Bank: a computer-based archival file for macromolecular structures

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7 January 2021

Basic local alignment search tool

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

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7 January 2021

Checking your imagination: applications of the free R value

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7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

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7 January 2021

Standard conformations for the canonical structures of immunoglobulins

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7 January 2021

Environment and exposure to solvent of protein atoms. Lysozyme and insulin

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7 January 2021

catELISA: a facile general route to catalytic antibodies

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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7 January 2021

The CCP4 suite: programs for protein crystallography

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7 January 2021