Vam7p YGL212W (Q27552554)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32912

synaptosomal vesicle fusion pore

1 reference

Transporter Classification Database ID

1.F.1.1.2

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Phox homologous domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Target SNARE coiled-coil homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

phosphatidylinositol binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IEA

SNAP receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

9 references

14 February 2019

The V-ATPase proteolipid cylinder promotes the lipid-mixing stage of SNARE-dependent fusion of yeast vacuoles.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Trans-SNARE complex assembly and yeast vacuole membrane fusion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

The phox homology (PX) domain protein interaction network in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Three v-SNAREs and two t-SNAREs, present in a pentameric cis-SNARE complex on isolated vacuoles, are essential for homotypic fusion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Sequential analysis of trans-SNARE formation in intracellular membrane fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

phosphatidylinositol-3-phosphate binding

IPI

2 references

14 February 2019

The Central Polybasic Region of the Soluble SNARE (Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor) Vam7 Affects Binding to Phosphatidylinositol 3-Phosphate by the PX (Phox Homology) Domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

A conserved domain is present in different families of vesicular fusion proteins: a new superfamily

IDA

SNAP receptor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

fungal-type vacuole membrane

IEA

4 references

10 September 2018

Molecular mechanism of membrane docking by the Vam7p PX domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32912&geneProductId=UniProtKB:P32912

10 September 2018

How and why intralumenal membrane fragments form during vacuolar lysosome fusion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32912&geneProductId=UniProtKB:P32912

10 September 2018

Molecular mechanism of membrane docking by the Vam7p PX domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32912&geneProductId=UniProtKB:P32912

10 September 2018

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32912&geneProductId=UniProtKB:P32912

integral component of membrane

IDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

The Atg17-Atg31-Atg29 Complex Coordinates with Atg11 to Recruit the Vam7 SNARE and Mediate Autophagosome-Vacuole Fusion

phagophore assembly site

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

3 references

14 February 2019

Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

fungal-type vacuole membrane

5 references

14 February 2019

Molecular mechanism of membrane docking by the Vam7p PX domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Molecular mechanism of membrane docking by the Vam7p PX domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

How and why intralumenal membrane fragments form during vacuolar lysosome fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

1 reference

5 June 2018

Compartmental specificity of cellular membrane fusion encoded in SNARE proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32912&geneProductId=UniProtKB:P32912

piecemeal microautophagy of the nucleus

IDA

1 reference

14 February 2019

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

1 reference

14 February 2019

A genomic screen for yeast mutants defective in selective mitochondria autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

cytoplasm to vacuole transport by the Cvt pathway

IMP

1 reference

14 February 2019

A genomic screen for yeast mutants defective in selective mitochondria autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

vacuole fusion, non-autophagic

IMP

2 references

14 February 2019

Stringent 3Q.1R composition of the SNARE 0-layer can be bypassed for fusion by compensatory SNARE mutation or by lipid bilayer modification.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

14 February 2019

Stringent 3Q.1R composition of the SNARE 0-layer can be bypassed for fusion by compensatory SNARE mutation or by lipid bilayer modification.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

autophagosome-lysosome fusion

1 reference

14 February 2019

The Atg17-Atg31-Atg29 Complex Coordinates with Atg11 to Recruit the Vam7 SNARE and Mediate Autophagosome-Vacuole Fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

intracellular protein transport

IMP

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32912

Target SNARE coiled-coil homology domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32912

Phox homologous domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32912

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Transporter Classification Database ID

1 reference

20 March 2022

1.F.1.1.2

2 references

Transporter Classification database

retrieved

13 March 2020