18S rRNA pseudouridine methyltransferase YLR186W (Q27550506)

http://www.ebi.ac.uk/interpro/protein/Q06287

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

5 references

9 May 2019

90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The small-subunit processome is a ribosome assembly intermediate

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

rRNA (pseudouridine) methyltransferase activity

IBA

5 references

27 March 2018

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

27 March 2018

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

27 March 2018

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

27 March 2018

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

27 March 2018

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

identical protein binding

EXP

2 references

9 May 2019

The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

rRNA (pseudouridine) methyltransferase activity

IPI

6 references

9 May 2019

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

10 September 2018

Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Nep1p (Emg1p), a novel protein conserved in eukaryotes and archaea, is involved in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

Nep1p (Emg1p), a novel protein conserved in eukaryotes and archaea, is involved in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

10 September 2018

Genetic interactions of yeast NEP1 (EMG1), encoding an essential factor in ribosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

The small-subunit processome is a ribosome assembly intermediate

IDA

small-subunit processome

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The small-subunit processome is a ribosome assembly intermediate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

IBA

biological process

1 reference

9 May 2019

The small-subunit processome is a ribosome assembly intermediate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

IEA

1 reference

9 May 2019

The small-subunit processome is a ribosome assembly intermediate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

IMP

rRNA base methylation

2 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

27 March 2018

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06287&geneProductId=UniProtKB:Q06287

endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

IMP

1 reference

9 May 2019

The small-subunit processome is a ribosome assembly intermediate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

TAS

rRNA base methylation

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06287

IBA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference