DNA-(apurinic or apyrimidinic site) lyase APN1 YKL114C (Q27548552)

Xylose isomerase-like superfamily

1 reference

stated in

Xylose isomerase-like, TIM barrel domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

AP endonuclease 2, zinc binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

double-stranded DNA 3'-5' exodeoxyribonuclease activity

1 reference

9 May 2019

The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

phosphoric diester hydrolase activity

1 reference

16 July 2018

Yeast DNA diesterase for 3'-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

3'-tyrosyl-DNA phosphodiesterase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

3'-5'-exodeoxyribonuclease activity

1 reference

9 May 2019

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

IDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

DNA-(apurinic or apyrimidinic site) endonuclease activity

4 references

16 July 2018

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

16 July 2018

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

16 July 2018

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

16 July 2018

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

1 reference

21 June 2018

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

DNA-(apurinic or apyrimidinic site) endonuclease activity

IPI

5 references

14 February 2019

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

14 February 2019

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

14 February 2019

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

14 February 2019

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

DNA-(apurinic or apyrimidinic site) endonuclease activity

IBA

4 references

9 May 2019

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

9 May 2019

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

9 May 2019

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

1 reference

16 July 2018

Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

16 July 2018

Intracellular localization of the Apn1 DNA repair enzyme of Saccharomyces cerevisiae. Nuclear transport signals and biological role.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

16 July 2018

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

9 May 2019

Intracellular localization of the Apn1 DNA repair enzyme of Saccharomyces cerevisiae. Nuclear transport signals and biological role.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

9 May 2019

Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1.

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

cellular response to DNA damage stimulus

IBA

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

1 reference

16 July 2018

Molecular mechanism of base excision repair of uracil-containing DNA in yeast cell-free extracts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22936&geneProductId=UniProtKB:P22936

nucleic acid phosphodiester bond hydrolysis

IDA

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22936

AP endonuclease 2, zinc binding site

has part(s)

1 reference

stated in

Xylose isomerase-like, TIM barrel domain

1 reference

stated in

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference