Structural Determinant of Human La Protein Critical for Internal Initiation of Translation of Hepatitis C Virus RNA (Q27487336)

2

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Asit Kumar Manna

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Romi Gupta

4

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Siddhartha Roy

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Saumitra Das

A peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation

6

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publication date

December 2008

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published in

Journal of Virology

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volume

82

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issue

23

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page(s)

11927-38

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cites work

1 reference

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A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation

20 March 2017

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Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element

20 March 2017

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Mechanism of ribosome recruitment by hepatitis C IRES RNA

20 March 2017

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

20 March 2017

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A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs

20 March 2017

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Internal ribosome entry sites in eukaryotic mRNA molecules

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Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

20 March 2017

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Recognition of nascent RNA by the human La antigen: conserved and divergent features of structure and function

20 March 2017

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20 March 2017

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Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein

20 March 2017

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A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein

20 March 2017

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La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate

20 March 2017

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Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication

29 September 2017

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La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro

29 September 2017

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La protein binding at the GCAC site near the initiator AUG facilitates the ribosomal assembly on the hepatitis C virus RNA to influence internal ribosome entry site-mediated translation

29 September 2017

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Targeting internal ribosome entry site (IRES)-mediated translation to block hepatitis C and other RNA viruses

29 September 2017

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Contributions of the individual domains in human La protein to its RNA 3'-end binding activity

29 September 2017

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Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery

29 September 2017

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Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation

29 September 2017

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B cell lymphokines in human systemic lupus erythematosus

29 September 2017

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Product inhibition of the hepatitis C virus NS3 protease

29 September 2017

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A novel, sensitive, and specific RT-PCR technique for quantitation of hepatitis C virus replication

2 June 2018

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Hepatitis C virus RNA replication is resistant to tumour necrosis factor-alpha

27 November 2018

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Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen

27 November 2018

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Aib-based peptide backbone as scaffolds for helical peptide mimics

27 November 2018

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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics.

27 November 2018

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Ribosomal protein S5 interacts with the internal ribosomal entry site of hepatitis C virus

27 November 2018

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