Pyrophosphorolytic Excision of Nonobligate Chain Terminators by Hepatitis C Virus NS5B Polymerase (Q27480921)

2

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Claudia M D'Abramo

3

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Luciano Cellai

4

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Matthias Götte

Antimicrobial Agents and Chemotherapy

5

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language of work or name

English

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publication date

August 2007

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published in

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volume

51

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issue

8

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page(s)

2920-8

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cites work

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29 September 2017

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Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes

2 June 2018

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DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Effect of pyrophosphorolysis and metal ions.

2 June 2018

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A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B.

2 June 2018

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Impact of the translocational equilibrium of HIV-1 reverse transcriptase on the efficiency of mismatch extensions and the excision of mispaired nucleotides

27 November 2018

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Excision of incorporated nucleotide analogue chain-terminators can diminish their inhibitory effects on viral RNA-dependent RNA polymerases

27 November 2018

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Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis

27 November 2018

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Multiple interactions within the hepatitis C virus RNA polymerase repress primer-dependent RNA synthesis

27 November 2018

1 reference

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Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance

27 November 2018

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Canonical 3'-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase

27 November 2018

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Arresting initiation of hepatitis C virus RNA synthesis using heterocyclic derivatives.

27 November 2018

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A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase

27 November 2018

1 reference

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Peginterferon alfa-2a in patients with chronic hepatitis C.

27 November 2018

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27 November 2018

Identifiers

DOI

10.1128/AAC.00186-07

1 reference

release_6wxfryqw2felrm2fkwp6ctrceu

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

17502402

1 reference