In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor (Q27473320)

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31 October 2019

title

In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor (English)

1 reference

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31 October 2019

0 references

1 reference

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5

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31 October 2019

Raffaele De Francesco

11

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author name string

Caterina Trozzi

1

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31 October 2019

Linda Bartholomew

2

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31 October 2019

Alessandra Ceccacci

3

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31 October 2019

Gabriella Biasiol

4

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31 October 2019

Sergio Altamura

6

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31 October 2019

Frank Narjes

7

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31 October 2019

Ester Muraglia

8

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31 October 2019

Giacomo Paonessa

9

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31 October 2019

Uwe Koch

10

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31 October 2019

Christian Steinkuhler

12

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31 October 2019

Giovanni Migliaccio

13

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31 October 2019

publication date

1 March 2003

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31 October 2019

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31 October 2019

volume

77

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31 October 2019

issue

6

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31 October 2019

page(s)

3669-3679

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Regulation of PKR and IRF-1 during hepatitis C virus RNA replication

31 October 2019

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21 March 2017

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21 March 2017

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21 March 2017

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21 March 2017

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21 March 2017

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21 March 2017

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The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism

21 March 2017

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Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

21 March 2017

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Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides

21 March 2017

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

21 March 2017

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The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

21 March 2017

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21 March 2017

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Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase

21 March 2017

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Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing

21 March 2017

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An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A

21 March 2017

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Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

21 March 2017

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A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

21 March 2017

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21 March 2017

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21 March 2017

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

21 March 2017

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21 March 2017

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21 March 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Solution structure of substrate-based ligands when bound to hepatitis C virus NS3 protease domain.

27 November 2018

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Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies

27 November 2018

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27 November 2018

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Substrate specificity of the hepatitis C virus serine protease NS3.

27 November 2018

1 reference

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Treatment of chronic viral hepatitis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12610142

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.77.6.3669-3679.2003

1 reference

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31 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610142%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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