Genealogical evidence for positive selection in the nef gene of HIV-1 (Q27473192)

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object named as

P M Zanotto

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Edward C. Holmes

4

object named as

E C Holmes

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author name string

E G Kallas

2

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R F de Souza

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

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language of work or name

English

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publication date

November 1999

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published in

Genetics

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volume

153

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issue

3

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page(s)

1077-89

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cites work

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Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions

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Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

21 March 2017

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A codon-based model of nucleotide substitution for protein-coding DNA sequences

21 March 2017

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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

21 March 2017

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Positive Darwinian evolution in human influenza A viruses

21 March 2017

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

21 March 2017

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Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

7 April 2017

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

7 April 2017

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Parallel evolution of drug resistance in HIV: failure of nonsynonymous/synonymous substitution rate ratio to detect selection

7 April 2017

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Characterization of the viral population during primary HIV-1 infection

29 September 2017

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Human immunodeficiency virus type 1 populations in blood and semen

29 September 2017

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Genetic drift can dominate short-term human immunodeficiency virus type 1 nef quasispecies evolution in vivo

29 September 2017

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Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population

29 September 2017

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HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women

29 September 2017

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Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase

29 September 2017

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Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase

29 September 2017

1 reference

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Intensity of natural selection at the major histocompatibility complex loci.

29 September 2017

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Estimating effective population size and mutation rate from sequence data using Metropolis-Hastings sampling.

29 September 2017

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Conservation of cytotoxic T lymphocyte (CTL) epitopes as a host strategy to constrain parasite adaptation: evidence from the nef gene of human immunodeficiency virus 1 (HIV-1).

29 September 2017

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Genetic drift of human immunodeficiency virus type 1?

2 June 2018

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Episodic adaptive evolution of primate lysozymes.

2 June 2018

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An arbovirus cline across the northern hemisphere

2 June 2018

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HIV-1 evolution and disease progression.

2 June 2018

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

19 June 2018

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T cell responses and viral escape

19 June 2018

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T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

27 November 2018

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Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

27 November 2018

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A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

27 November 2018

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Large-scale search for genes on which positive selection may operate.

27 November 2018

1 reference

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27 November 2018

Causes of HIV diversity

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Estimating synonymous and nonsynonymous substitution rates

27 November 2018

1 reference

12 December 2020

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1 reference

12 December 2020

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

12 December 2020

Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression

1 reference

12 December 2020