Suppression of Rap1 impairs cardiac myofibrils and conduction system in zebrafish (Q27332751)

RAP1B, member of RAS oncogene family

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Wei Dong

1

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Zhenglin Yang

2

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Fan Yang

3

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Jialiang Wang

4

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Yan Zhuang

5

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Chongren Xu

6

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Bo Zhang

7

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Xiao-Li Tian

8

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Dong Liu

Creative Commons Attribution 4.0 International

9

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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page(s)

e50960

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issue

11

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copyright license

start time

30 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3511394/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

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Rap1 GTPases: an emerging role in the cardiovasculature

21 March 2017

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Slow ventricular conduction in mice heterozygous for a connexin43 null mutation

21 March 2017

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Role of Epac in brain and heart

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Zebrafish as a model to study cardiac development and human cardiac disease

28 September 2017

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Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells

28 September 2017

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The cAMP binding protein Epac regulates cardiac myofilament function

28 September 2017

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Functional characterization of the cAMP-binding proteins Epac in cardiac myocytes

28 September 2017

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Cell-cell junction formation: the role of Rap1 and Rap1 guanine nucleotide exchange factors

28 September 2017

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Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke

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The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors

28 September 2017

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Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart

28 September 2017

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Activation of Epac stimulates integrin-dependent homing of progenitor cells

28 September 2017

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A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein.

28 September 2017

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Rap1: a key regulator in cell-cell junction formation

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Rap1 regulates E-cadherin-mediated cell-cell adhesion

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Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

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The role of Rap1 in integrin-mediated cell adhesion

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Rap1 signalling: adhering to new models

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Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion

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Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect.

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050960

Epac and phospholipase Cepsilon regulate Ca2+ release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II.

21 January 2018

1 reference

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Functional and structural assessment of intercellular communication. Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytes

27 November 2018

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12 December 2020

Enhanced functional gap junction neoformation by protein kinase A-dependent and Epac-dependent signals downstream of cAMP in cardiac myocytes

1 reference

12 December 2020

The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes

1 reference

12 December 2020

Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes

1 reference

12 December 2020

[Electrophysiological characterization of connexin 40 deficient hearts--in vivo studies in mice]

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0050960

Identifiers

DOI

1 reference

415877

ADS bibcode

2012PLoSO...750960D

0 references

415877

1 reference

1 reference

1 reference