Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes (Q27330350)

26 June 2017

Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes (English)

1 reference

26 June 2017

1 reference

GOA release 2020-03-11

Vps38p YLR360W

1 reference

GOA release 2020-03-11

author

Jan Steyaert

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Roger L. Williams

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Nicolas Soler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Yohei Ohashi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Els Pardon

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

John E Burke

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Glenn R Masson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

10

Nicholas T Ktistakis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Ksenia Rostislavleva

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Lufei Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Chris Johnson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

1 October 2015

1 reference

26 June 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

350

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

6257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

aac7365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4601532/fullTextXML

inferred from PubMed Central ID database lookup

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Resistance to inhibitors of cholinesterase (Ric)-8A and Gαi contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps)34 activity

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Crystal structure of Prp8 reveals active site cavity of the spliceosome

21 March 2017

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Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG

21 March 2017

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Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein

21 March 2017

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A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence

21 March 2017

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21 March 2017

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A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

21 March 2017

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Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34

21 March 2017

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21 March 2017

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Structure and Function of Vps15 in the Endosomal G Protein Signaling Pathway ,

21 March 2017

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DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

21 March 2017

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The HHpred interactive server for protein homology detection and structure prediction

21 March 2017

1 reference

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Human VPS34 and p150 are Rab7 Interacting Partners

21 March 2017

1 reference

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Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae

21 March 2017

1 reference

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Experimental phasing with SHELXC/D/E: combining chain tracing with density modification

21 March 2017

1 reference

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21 March 2017

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Phasercrystallographic software

21 March 2017

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BALBES: a molecular-replacement pipeline

21 March 2017

1 reference

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Automated structure solution with autoSHARP

21 March 2017

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Methods used in the structure determination of bovine mitochondrial F1 ATPase

21 March 2017

1 reference

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Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity

21 March 2017

1 reference

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Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy

21 March 2017

1 reference

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Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

21 March 2017

1 reference

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Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

21 March 2017

1 reference

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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

21 March 2017

1 reference

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Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases

21 March 2017

1 reference

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Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis

21 March 2017

1 reference

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Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Beclin 1 regulates growth factor receptor signaling in breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

A general protocol for the generation of Nanobodies for structural biology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

AMPK connects energy stress to PIK3C3/VPS34 regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Novel somatic mutations to PI3K pathway genes in metastatic melanoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Evolution of the eukaryotic protein kinases as dynamic molecular switches

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Negative regulation of Vps34 by Cdk mediated phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

28 September 2017

Know your dose: RADDOSE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Robotic nanolitre protein crystallisation at the MRC Laboratory of Molecular Biology.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601532

Bio3d: an R package for the comparative analysis of protein structures.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7365

The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26450213

12 December 2020

inferred from PubMed ID database lookup

Role of Rab5 in the Recruitment of hVps34/p150 to the Early Endosome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26450213

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCIENCE.AAC7365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

release_s7222t3t5jds7f5zbxf72rhek4

4 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/s7222t3t5jds7f5zbxf72rhek4

24 November 2022

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1017933

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1017933

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450213%20AND%20SRC:MED&resulttype=core&format=json