Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo (Q27330038)

11

0 references

Lukas Kenner

object named as

Lukas Kenner

9

0 references

Mathias Müller

object named as

Mathias Müller

12

0 references

author name string

Nicole R Leitner

1

0 references

Caroline Lassnig

2

0 references

Rita Rom

3

0 references

Susanne Heider

4

0 references

Zsuzsanna Bago-Horvath

5

0 references

Simone Müller

7

0 references

Thomas Kolbe

8

0 references

Thomas Rülicke

Creative Commons Attribution 4.0 International

10

0 references

language of work or name

English

0 references

publication date

2014

0 references

published in

PLOS One

0 references

volume

9

0 references

issue

1

0 references

page(s)

e86608

0 references

copyright license

start time

29 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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TYK2 kinase activity is required for functional type I interferon responses in vivo

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

7 April 2017

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The tumor suppressor function of STAT1 in breast cancer

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Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis

28 September 2017

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Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome

28 September 2017

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Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival.

28 September 2017

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Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

28 September 2017

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STATs shape the active enhancer landscape of T cell populations

28 September 2017

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Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

28 September 2017

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STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

28 September 2017

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Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias

28 September 2017

1 reference

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Reviewing host proteins of Rhabdoviridae: possible leads for lesser studied viruses

28 September 2017

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Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

28 September 2017

1 reference

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STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

28 September 2017

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A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice

28 September 2017

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Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation

28 September 2017

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28 September 2017

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Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden.

28 September 2017

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Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling

28 September 2017

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A novel form of human STAT1 deficiency impairing early but not late responses to interferons

28 September 2017

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Experimental encephalomyocarditis virus infection in small laboratory rodents

28 September 2017

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Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

28 September 2017

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Tumor-promoting role of signal transducer and activator of transcription (Stat)1 in late-stage melanoma growth.

28 September 2017

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STAT1 and pathogens, not a friendly relationship

28 September 2017

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Rhabdovirus evasion of the interferon system

28 September 2017

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Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

28 September 2017

1 reference

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A partial form of recessive STAT1 deficiency in humans

28 September 2017

1 reference

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STAT2 hypomorphic mutant mice display impaired dendritic cell development and antiviral response.

28 September 2017

1 reference

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Recruitment of Stat1 to chromatin is required for interferon-induced serine phosphorylation of Stat1 transactivation domain

28 September 2017

1 reference

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High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells.

28 September 2017

1 reference

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A time- and dose-dependent STAT1 expression system

28 September 2017

1 reference

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Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain

28 September 2017

1 reference

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STAT1 acts as a tumor promoter for leukemia development

28 September 2017

1 reference

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Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo

28 September 2017

1 reference

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The yin and yang of type I interferon activity in bacterial infection

28 September 2017

1 reference

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Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

28 September 2017

1 reference

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Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells

28 September 2017

1 reference

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STAT1-induced apoptosis is mediated by caspases 2, 3, and 7.

28 September 2017

1 reference

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Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

28 September 2017

1 reference

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Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways

28 September 2017

1 reference

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Partial impairment of cytokine responses in Tyk2-deficient mice

28 September 2017

1 reference

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Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes

28 September 2017

1 reference

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

28 September 2017

1 reference

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Macrophages from endotoxin-hyporesponsive (Lpsd) C3H/HeJ mice are permissive for vesicular stomatitis virus because of reduced levels of endogenous interferon: possible mechanism for natural resistance to virus infection

28 September 2017

1 reference

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Tet-Transgenic Rodents: a comprehensive, up-to date database

28 September 2017

1 reference

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High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice

2 June 2018

1 reference

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Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906053

The clinical spectrum of patients with deficiency of Signal Transducer and Activator of Transcription-1.

2 June 2018

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Novel STAT1 alleles in a patient with impaired resistance to mycobacteria.

21 January 2018

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MMTV-neu mice deficient in STAT1 are susceptible to develop ovarian teratomas.

21 January 2018

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Differential expression of immune-related markers in breast cancer by molecular phenotypes.

21 January 2018

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Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

21 January 2018

1 reference

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Local type I IFN receptor signaling protects against virus spread within the central nervous system

21 January 2018

1 reference

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Viral replication in olfactory receptor neurons and entry into the olfactory bulb and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086608

Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.

21 January 2018

1 reference

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Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes

21 January 2018

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21 January 2018

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IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism

27 November 2018

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Polymorphic microsatellite markers in the outbred CFW and ICR stocks for the generation of speed congenic mice on C57BL/6 background

21 January 2018

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Generation of mice with a conditional Stat1 null allele

21 January 2018

1 reference

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Autosomal-Dominant Chronic Mucocutaneous Candidiasis with STAT1-Mutation can be Complicated with Chronic Active Hepatitis and Hypothyroidism

21 January 2018

1 reference

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The power of reversibility regulating gene activities via tetracycline-controlled transcription

21 January 2018

1 reference

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Comparison of distribution of doxycycline in mice after oral and intravenous application measured by a high-performance liquid chromatographic method

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24489749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immune response in Stat2 knockout mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24489749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Blood and organ concentrations of tetracycline and doxycycline in female mice. Comparison to males

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24489749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0086608

1 reference

4828416

ADS bibcode

2014PLoSO...986608L

0 references

4828416

1 reference

1 reference

1 reference