Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models (Q27301158)

3

object named as

Laurent Mouchiroud

0 references

Vincenzo Sorrentino

object named as

Vincenzo Sorrentino

4

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author name string

Matteo Cornaglia

1

0 references

Gopalan Krishnamani

2

0 references

Thomas Lehnert

5

0 references

Martin A M Gijs

Molecular Neurodegeneration

7

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language of work or name

English

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publication date

2016

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published in

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volume

11

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issue

1

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page(s)

17

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exact match

https://scigraph.springernature.com/pub.10.1186/s13024-016-0083-6

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C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging

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The cell-non-autonomous nature of electron transport chain-mediated longevity

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The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

7 April 2017

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Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes

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The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

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Mitonuclear protein imbalance as a conserved longevity mechanism

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28 September 2017

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Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration

28 September 2017

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28 September 2017

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Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

28 September 2017

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31 May 2018

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Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans

21 January 2018

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Maze exploration and learning in C. elegans.

21 January 2018

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Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies.

21 January 2018

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C.L.I.P.--continuous live imaging platform for direct observation of C. elegans physiological processes.

21 January 2018

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Undulatory swimming in viscoelastic fluids.

21 January 2018

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Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-016-0083-6

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-016-0083-6

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-016-0083-6

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-016-0083-6

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-016-0083-6

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

21 January 2018

1 reference

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Amyloid-beta (Aβ1-42)-induced paralysis in Caenorhabditis elegans is reduced by restricted cholesterol supply.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-016-0083-6

A Systematic RNAi Screen of Neuroprotective Genes Identifies Novel Modulators of Alpha-Synuclein-Associated Effects in Transgenic Caenorhabditis elegans.

21 January 2018

1 reference

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Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26858201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26858201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S13024-016-0083-6

1 reference

Dimensions Publication ID

2838477

1024452793

0 references

2838477

1 reference

1 reference

1 reference