holomycin (Q27258732)

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chemical compound
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Language Label Description Also known as
English
holomycin
chemical compound

    Statements

    mass
    213.987±0 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    10262683
    language of work or name
    English
    title
    HOLOMYCIN (English)
    retrieved
    14 October 2016
    chemical formula
    C₇H₆N₂O₂S₂
    1 reference
    stated in
    PubChem
    PubChem CID
    10262683
    language of work or name
    English
    title
    HOLOMYCIN (English)
    retrieved
    14 October 2016
    canonical SMILES
    CC(=O)NC1=C2C(=CSS2)NC1=O
    1 reference
    stated in
    PubChem
    PubChem CID
    10262683
    language of work or name
    English
    title
    HOLOMYCIN (English)
    retrieved
    14 October 2016
    found in taxon
    Streptomyces clavuligerus
    13 references
    stated in
    Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus
    stated in
    A backup plan for self-protection: S-methylation of holomycin biosynthetic intermediates in Streptomyces clavuligerus
    stated in
    Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites.
    stated in
    Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1.
    stated in
    The Pathway-Specific Regulator ClaR of Streptomyces clavuligerus Has a Global Effect on the Expression of Genes for Secondary Metabolism and Differentiation
    stated in
    Role of the cmcH-ccaR intergenic region and ccaR overexpression in cephamycin C biosynthesis in Streptomyces clavuligerus
    stated in
    Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction
    stated in
    Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways
    stated in
    Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis
    stated in
    Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus
    stated in
    Transcriptional analysis and proteomics of the holomycin gene cluster in overproducer mutants of Streptomyces clavuligerus
    stated in
    Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus
    stated in
    Transcriptional Studies on a Streptomyces clavuligerus oppA2 Deletion Mutant: N-Acetylglycyl-Clavaminic Acid Is an Intermediate of Clavulanic Acid Biosynthesis

    Identifiers

    ChemSpider ID
    8438162
    1 reference
    stated in
    ChemSpider
    ChemSpider ID
    8438162
    language of work or name
    English
    title
    6-Acetamido-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one (English)
    retrieved
    14 October 2016
     
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