(Z)-ligustilide (Q27136725)

Ligustilide (English)

7 October 2016

chemical formula

C₁₂H₁₄O₂

1 reference

Ligustilide (English)

7 October 2016

canonical SMILES

CCCC=C1C2=C(C=CCC2)C(=O)O1

1 reference

Ligustilide (English)

7 October 2016

isomeric SMILES

CCC/C=C\1/C2=C(C=CCC2)C(=O)O1

1 reference

Liquid chromatographic–electrospray mass spectrometric study of the phthalides of Angelica sinensis and chemical changes of Z-ligustilide

Ligustilide (English)

7 October 2016

16 references

Dong quai

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis

Dong Quai

Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats.

Screening and analysis of permeable compounds in Radix Angelica Sinensis with immobilized liposome chromatography

Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis

Dynamic nature of the ligustilide complex.

Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1.

Analysis and processing of Chinese herbal drugs; VI. The study of Angelicae radix.

Copper = Leslie M. Klevay

Quality Evaluation of Angelica sinensis by Simultaneous Determination of Ten Compounds Using LC-PDA

Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis

Identification and comparative quantification of bio-active phthalides in essential oils from si-wu-tang, fo-shou-san, radix angelica and rhizoma chuanxiong.

Cytotoxic constituents from angelicae sinensis radix

Ligusticum porteri

9 references

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Addition of methyl thioglycolate and benzylamine to (Z)-ligustilide, a bioactive unsaturated lactone constituent of several herbal medicines. An improved synthesis of (Z)-ligustilide

Phthalides and monoterpenes of the hexane extracts of the roots of Ligusticum porterei, L. filicinum and L. tennuifolium

Phthalides and Monoterpenes of the Hexane Extract of the Roots of Ligusticum porteri1

(Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor.

(Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor.

Secondary Metabolites from the Roots of Ligusticum porteri (Umbelliferae). X-Ray Structure of Z-6.6',7.3a'-Diligustilide

(1)H and DOSY NMR spectroscopy analysis of Ligusticum porteri rhizome extracts

Phthalides and other constituents from Ligusticum porteri; sedative and spasmolytic activities of some natural products and derivatives

Ligusticum chuanxiong

8 references

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong)

HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong

Two phthalides from Ligusticum chuangxiong

Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry

Separation and Purification of Z Ligustilide and Senkyunolide A fromLigusticum chuanxiongHort. with Supercritical Fluid Extraction and High‐Speed Counter‐Current Chromatography

Studies on the baths with crude drug: the effects of Senkyu extract as skin penetration enhancer

Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong

Angelica acutiloba

6 references

Effects of methylenechloride-soluble fraction of Japanese angelica root extract, ligustilide and butylidenephthalide, on pentobarbital sleep in group-housed and socially isolated mice.

Reduced Inhomogeneity of Angelica acutiloba Plants Propagated Clonally Through Somatic Embryoids

Analysis and processing of Chinese herbal drugs; VI. The study of Angelicae radix.

Evaluation of Angelicae Radix (Touki) by the Inhibitory Effect on Platelet Aggregation

STUDIES ON THE CONSTITUENTS OF UMBELLIFERAE PLANTS. VIII. DISTRIBUTION OF ALKYLPHTHALIDES IN UMBELLIFERAE PLANTS

Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila melanogaster

celery

6 references

GC/MS and GC/FTIR Analysis of the Essential Oil of Celery Seed

STUDIES ON THE CONSTITUENTS OF UMBELLIFERAE PLANTS. VIII. DISTRIBUTION OF ALKYLPHTHALIDES IN UMBELLIFERAE PLANTS

Phytochemical and biological characterization of Italian "sedano bianco di Sperlonga" Protected Geographical Indication celery ecotype: A multimethodological approach

Effect of nitrogen fertilizers on celery volatiles

Free and glycosidically bound volatile compounds in fresh celery (Apium graveolens L.)

Aromatic Volatile Composition of Celery and Celeriac Cultivars

Krubera peregrina

1 reference

Phthalides in Roots of Capnophyllum peregrinum and Peucedanum ostruthium

Ligusticum filicinum

1 reference

Phthalides and monoterpenes of the hexane extracts of the roots of Ligusticum porterei, L. filicinum and L. tennuifolium

Ligusticum tenuifolium

1 reference

Phthalides and monoterpenes of the hexane extracts of the roots of Ligusticum porterei, L. filicinum and L. tennuifolium

parsley

1 reference

3-Butyl-5,6-dihydro-4H-isobenzofuran-1-one, a sensorial active phthalide in parsley roots

Peucedanum ostruthium

1 reference

Phthalides in Roots of Capnophyllum peregrinum and Peucedanum ostruthium

Scutellaria baicalensis

1 reference

Essential oil of Scutellaria baicalensis G.

Trachyspermum roxburghianum

1 reference

Volatile Seed Oils ofTrachyspermum roxburghianumBenth. ex. Kurz. from India

Angelica glauca

1 reference

Angeolide, a Novel Lactone fromAngelica glauca

Apiaceae

6 references

Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-kappaB pathway in primary rat microglia

Components of Cnidium officinale Makino: occurrence of pregnenolone, coniferyl ferulate, and hydroxyphthalides

STUDIES ON THE CONSTITUENTS OF UMBELLIFERAE PLANTS. VIII. DISTRIBUTION OF ALKYLPHTHALIDES IN UMBELLIFERAE PLANTS

Studies on the baths with crude drug: the effects of Senkyu extract as skin penetration enhancer

[Centrally acting muscle relaxant effect of phthalides (ligustilide, cnidilide and senkyunolide) obtained from Cnidium officinale Makino]

[Studies on chemical protectors against radiation. XXX. Radioprotective substances of cnidii rhizoma]

Opopanax chironius

1 reference

Phthalides in Roots of Opopanax chironium

Conioselinum anthriscoides

8 references

Two phthalides from Ligusticum chuangxiong

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry

Separation and Purification of Z Ligustilide and Senkyunolide A fromLigusticum chuanxiongHort. with Supercritical Fluid Extraction and High‐Speed Counter‐Current Chromatography

Studies on the baths with crude drug: the effects of Senkyu extract as skin penetration enhancer

Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong)

HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong

Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong

Ligusticum striatum

8 references

Two phthalides from Ligusticum chuangxiong

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry

Separation and Purification of Z Ligustilide and Senkyunolide A fromLigusticum chuanxiongHort. with Supercritical Fluid Extraction and High‐Speed Counter‐Current Chromatography

Studies on the baths with crude drug: the effects of Senkyu extract as skin penetration enhancer

Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong)

HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong

Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong

Levisticum officinale

6 references

Growth, Yield and Essential Oil of Lovage Grown in Finland

Influence of Harvesting Time on the Composition of Volatile Components in Different Anatomical Parts of Lovage (Levisticum officinaleKoch.)

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Ligustilide: Guiding Component for Preparations of Levisticum officinale Roots

ChemInform Abstract: NEW CONSTITUENTS OF LEVISTICUM OFFICINALE KOCH

STUDIES ON THE CONSTITUENTS OF UMBELLIFERAE PLANTS. VIII. DISTRIBUTION OF ALKYLPHTHALIDES IN UMBELLIFERAE PLANTS

Oreocome striata

1 reference

Phthalides from the rhizome of Ligusticum wallichii

Identifiers

InChI

InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3/b11-8-

1 reference

Ligustilide (English)

IQVQXVFMNOFTMU-FLIBITNWSA-N

7 October 2016

InChIKey

2 references

Ligustilide (English)

7 October 2016

ChEBI release 2020-09-01

1 reference

(Z)-ligustilide (English)

7 October 2016

1 reference

(Z)-Ligustilide (English)

7 October 2016

1 reference

Ligustilide (English)

7 October 2016

ChEBI ID

68232

mapping relation type

1 reference

(Z)-ligustilide (English)

7 October 2016

1 reference

LIGUSTILIDE (English)

7 October 2016

1 reference

809-243-4

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.237.128

27 December 2018

ECHA Substance Infocard ID

[No public or meaningful name is available] (English)

quotation

CAS no.: 4431-01-0 (English)

100.237.128

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.237.128

27 December 2018

Human Metabolome Database ID

[No public or meaningful name is available] (English)

quotation

CAS no.: 4431-01-0 (English)

HMDB0302720

1 reference

based on heuristic

inferred from InChIKey

KNApSAcK ID

C00032553

1 reference

based on heuristic

inferred from InChIKey

C00051275

1 reference

based on heuristic

inferred from InChIKey

0 references

1 reference

(Z)-ligustilide (English)