Decoding the complexity of type I interferon to treat persistent viral infections (Q27023801)

Crossref

David G. Brooks

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

December 2013

1 reference

published in

Trends in Microbiology

1 reference

volume

21

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issue

12

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page(s)

634-40

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Immunomodulatory functions of type I interferons

cites work

1 reference

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A diverse range of gene products are effectors of the type I interferon antiviral response

21 March 2017

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Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

21 March 2017

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Functional role of type I and type II interferons in antiviral defense

21 March 2017

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Interferon signaling and treatment outcome in chronic hepatitis C

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 March 2017

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 March 2017

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 March 2017

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Virus interference. I. The interferon

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The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

21 March 2017

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The dsRNA protein kinase PKR: virus and cell control

21 March 2017

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Toll-like receptor signaling and IRF transcription factors

21 March 2017

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Mechanisms of type-I- and type-II-interferon-mediated signalling

21 March 2017

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Interferons, interferon-like cytokines, and their receptors

21 March 2017

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Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

21 March 2017

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Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection

21 March 2017

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Recruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2

21 March 2017

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Type I interferons in host defense

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Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion.

7 April 2017

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Persistent LCMV infection is controlled by blockade of type I interferon signaling

28 September 2017

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Monitoring cellular immune markers in HIV infection: from activation to exhaustion

28 September 2017

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Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration

28 September 2017

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Microbial translocation, immune activation, and HIV disease

28 September 2017

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IFN-α in the treatment of melanoma

28 September 2017

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Infected CD8α- dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection

28 September 2017

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Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled trial

28 September 2017

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Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection

28 September 2017

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Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection

28 September 2017

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Systematic identification of type I and type II interferon-induced antiviral factors

28 September 2017

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Type 1 interferons and antiviral CD8 T-cell responses

28 September 2017

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Blocking type I interferon production: a new therapeutic option to reduce the HIV-1-induced immune activation

28 September 2017

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Direct effects of type I interferons on cells of the immune system

28 September 2017

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Evolving expectations around early management of multiple sclerosis

28 September 2017

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Pathogenic mechanisms of HIV disease

28 September 2017

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Reduction of immune activation with chloroquine therapy during chronic HIV infection

28 September 2017

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Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial

28 September 2017

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Clinical and immunologic basis of interferon therapy in melanoma

28 September 2017

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Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

28 September 2017

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Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

28 September 2017

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Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation

28 September 2017

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Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques

28 September 2017

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Chronic innate immune activation as a cause of HIV-1 immunopathogenesis

28 September 2017

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Interferon, Mx, and viral countermeasures

28 September 2017

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Type I interferon receptors: biochemistry and biological functions.

28 September 2017

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Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T c

28 September 2017

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Type I interferon production in HIV-infected patients

28 September 2017

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Gene expression profiling in human autoimmunity.

28 September 2017

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

28 September 2017

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Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells

28 September 2017

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IFN-beta-1b inhibits IL-12 production in peripheral blood mononuclear cells in an IL-10-dependent mechanism: relevance to IFN-beta-1b therapeutic effects in multiple sclerosis

28 September 2017

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Initial and innate responses to viral infections--pattern setting in immunity or disease

28 September 2017

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Fascination with 2-5A-Dependent RNase: A Unique Enzyme That Functions in Interferon Action*

28 September 2017

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Purified interferon as protection against rhinovirus infection

28 September 2017

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Blockade of chronic type I interferon signaling to control persistent LCMV infection

28 September 2017

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Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy-treated immunologic nonresponders

31 May 2018

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Differential receptor subunit affinities of type I interferons govern differential signal activation.

31 May 2018

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Absence of clinical, virological, and immunological signs of progression in HIV-1-infected patients receiving active anti-interferon-alpha immunization: a 30-month follow-up report

31 May 2018

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The efficacy of intranasal interferon alpha-2a in respiratory syncytial virus infection in volunteers

31 May 2018

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25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end.

31 May 2018

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Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice

28 November 2018

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Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: results of a phase I, placebo-controlled, double-blind, dose-escalation study.

28 November 2018

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Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

28 November 2018

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Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon

28 November 2018

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Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment

28 November 2018

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Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection.

28 November 2018

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Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

28 November 2018

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Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis. 1997.

28 November 2018

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Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

28 November 2018

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Dendritic cells generated in the presence of granulocyte-macrophage colony-stimulating factor and IFN-alpha are potent inducers of HIV-specific CD8 T cells

28 November 2018

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12 December 2020

Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

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12 December 2020

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

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12 December 2020

Pharmacogenomics and translational simulations to bridge indications for an anti-interferon-α receptor antibody

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12 December 2020