Urinary tract infections: epidemiology, mechanisms of infection and treatment options (Q27022487)

Ana Lidia Flores-Mireles

series ordinal

1

object named as

Ana L. Flores-Mireles

1 reference

Jennifer N. Walker

2

1 reference

Michael Caparon

series ordinal

3

1 reference

language of work or name

1 reference

May 2015

1 reference

full work available at URL

https://www.nature.com/articles/nrmicro3432

archive URL

https://web.archive.org/web/20221013120652/https://www.nature.com/articles/nrmicro3432

archive date

13 October 2022

0 references

published in

Nature Reviews Microbiology

1 reference

volume

13

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page(s)

269-84

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issue

5

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Lu/BCAM adhesion glycoprotein is a receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

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28 September 2017

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Intracellular bacteria in the pathogenesis of Escherichia coli urinary tract infection in children

28 September 2017

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Forced resurgence and targeting of intracellular uropathogenic Escherichia coli reservoirs

28 September 2017

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Clinical complications of urinary catheters caused by crystalline biofilms: something needs to be done

28 September 2017

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28 September 2017

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Regulation of biofilm formation in Pseudomonas and Burkholderia species

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In silico and in vivo studies of truncated forms of flagellin (FliC) of enteroaggregative Escherichia coli fused to FimH from uropathogenic Escherichia coli as a vaccine candidate against urinary tract infections

28 September 2017

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Diagnosis, management, and prevention of catheter-associated urinary tract infections

28 September 2017

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Management of urinary tract infections from multidrug-resistant organisms

28 September 2017

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Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden

28 September 2017

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Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation

28 September 2017

1 reference

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28 September 2017

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Pilicides inhibit the FGL chaperone/usher assisted biogenesis of the Dr fimbrial polyadhesin from uropathogenic Escherichia coli

28 September 2017

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Role of Klebsiella pneumoniae type 1 and type 3 fimbriae in colonizing silicone tubes implanted into the bladders of mice as a model of catheter-associated urinary tract infections

28 September 2017

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28 September 2017

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28 September 2017

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Emerging resistance problems and future perspectives in pharmacotherapy for complicated urinary tract infections

28 September 2017

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28 September 2017

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28 September 2017

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Treatment of complicated urinary tract infections with an emphasis on drug-resistant gram-negative uropathogens

28 September 2017

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28 September 2017

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Molecular blueprint of uropathogenic Escherichia coli virulence provides clues toward the development of anti-virulence therapeutics

28 September 2017

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Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections

28 September 2017

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Cytotoxic necrotizing factor 1 and hemolysin from uropathogenic Escherichia coli elicit different host responses in the murine bladder

28 September 2017

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28 September 2017

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Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors

28 September 2017

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The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection.

28 September 2017

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The siderophore yersiniabactin binds copper to protect pathogens during infection

28 September 2017

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Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Proteus mirabilis biofilms and catheter-associated urinary tract infections

28 September 2017

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Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection

28 September 2017

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Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection

28 September 2017

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Uroplakins in the lower urinary tract

28 September 2017

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Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review

28 September 2017

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Redundancy and specificity of Escherichia coli iron acquisition systems during urinary tract infection

28 September 2017

1 reference

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Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli

28 September 2017

1 reference

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The epidemiology of urinary tract infection

28 September 2017

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Proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in Proteus mirabilis

28 September 2017

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Urinary tract infections caused by Pseudomonas aeruginosa: a minireview

28 September 2017

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Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infections.

28 September 2017

1 reference

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Host-pathogen interactions in urinary tract infection

28 September 2017

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A tale of two pili: assembly and function of pili in bacteria

28 September 2017

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Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence.

28 September 2017

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Waging war against uropathogenic Escherichia coli: winning back the urinary tract

28 September 2017

1 reference

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Structural biology of the chaperone-usher pathway of pilus biogenesis

28 September 2017

1 reference

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Mucosal immunization with iron receptor antigens protects against urinary tract infection

28 September 2017

1 reference

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Comparative structure-function analysis of mannose-specific FimH adhesins from Klebsiella pneumoniae and Escherichia coli

28 September 2017

1 reference

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TLR4-mediated expulsion of bacteria from infected bladder epithelial cells

28 September 2017

1 reference

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Cell biology and physiology of the uroepithelium

28 September 2017

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Oxygen-limiting conditions enrich for fimbriate cells of uropathogenic Proteus mirabilis and Escherichia coli.

28 September 2017

1 reference

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FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling

28 September 2017

1 reference

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Vaccination with proteus toxic agglutinin, a hemolysin-independent cytotoxin in vivo, protects against Proteus mirabilis urinary tract infection

28 September 2017

1 reference

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Characterization of Klebsiella pneumoniae type 1 fimbriae by detection of phase variation during colonization and infection and impact on virulence

28 September 2017

1 reference

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Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract

28 September 2017

1 reference

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Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression

28 September 2017

1 reference

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Complicated catheter-associated urinary tract infections due to Escherichia coli and Proteus mirabilis

28 September 2017

1 reference

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Morphological plasticity as a bacterial survival strategy

28 September 2017

1 reference

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Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline

28 September 2017

1 reference

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Detection of intracellular bacterial communities in human urinary tract infection

28 September 2017

1 reference

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LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis

28 September 2017

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Flagella allow uropathogenic Escherichia coli ascension into murine kidneys

28 September 2017

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Sticky fibers and uropathogenesis: bacterial adhesins in the urinary tract

28 September 2017

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Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli

28 September 2017

1 reference

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Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2

28 September 2017

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Differential stability and trade-off effects of pathoadaptive mutations in the Escherichia coli FimH adhesin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Functional analysis of antigen 43 in uropathogenic Escherichia coli reveals a role in long-term persistence in the urinary tract

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Use of translational fusion of the MrpH fimbrial adhesin-binding domain with the cholera toxin A2 domain, coexpressed with the cholera toxin B subunit, as an intranasal vaccine to prevent experimental urinary tract infection by Proteus mirabilis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

E. coli CNF1 toxin: a two-in-one system for host-cell invasion.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Characterization of Pseudomonas aeruginosa exoenzyme S as a bifunctional enzyme in J774A.1 macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Visualization of Proteus mirabilis within the matrix of urease-induced bladder stones during experimental urinary tract infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Urinary tract infections: disease panorama and challenges

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Pathogenesis of Proteus mirabilis urinary tract infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

The chaperone/usher pathway: a major terminal branch of the general secretory pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Basis for the selective antibacterial activity in vitro of proton pump inhibitors against Helicobacter spp.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Unique ability of the Proteus mirabilis capsule to enhance mineral growth in infectious urinary calculi

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Phospholipase C (heat-labile hemolysin) of Pseudomonas aeruginosa: purification and preliminary characterization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Genetic and biochemical diversity of ureases of Proteus, Providencia, and Morganella species isolated from urinary tract infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Staphylococcus saprophyticus urease: characterization and contribution to uropathogenicity in unobstructed urinary tract infection of rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Identification and characterization of the genes encoding the type 3 and type 1 fimbrial adhesins of Klebsiella pneumoniae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Alpha-hemolysin contributes to the pathogenicity of piliated digalactoside-binding Escherichia coli in the kidney: efficacy of an alpha-hemolysin vaccine in preventing renal injury in the BALB/c mouse model of pyelonephritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Virulence determinants in Pseudomonas aeruginosa strains from urinary tract infections

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Fimbriation, capsulation, and iron-scavenging systems of Klebsiella strains associated with human urinary tract infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Urease. The primary cause of infection-induced urinary stones

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Multiple virulence factors regulated by quorum sensing may help in establishment and colonisation of urinary tract by Pseudomonas aeruginosa during experimental urinary tract infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

The Isolation and the Biofilm Formation of Uropathogens in the Patients with Catheter Associated Urinary Tract Infections (UTIs).

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

A novel autotransporter of uropathogenic Proteus mirabilis is both a cytotoxin and an agglutinin

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Possible mechanism for the inhibition of gastric (H+ + K+)-adenosine triphosphatase by the proton pump inhibitor AG-1749.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

In vivo and in vitro toxicity of phospholipase C from Pseudomonas aeruginosa

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Diversity of the Escherichia coli type 1 fimbrial lectin. Differential binding to mannosides and uroepithelial cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Molecular detection of HpmA and HlyA hemolysin of uropathogenic Proteus mirabilis.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Activity of biapenem (RPX2003) combined with the boronate β-lactamase inhibitor RPX7009 against carbapenem-resistant Enterobacteriaceae

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Activity of BAL30072 alone or combined with β-lactamase inhibitors or with meropenem against carbapenem-resistant Enterobacteriaceae and non-fermenters

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Vaccination with recombinant FimH fused with flagellin enhances cellular and humoral immunity against urinary tract infection in mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Ambulatory medical care utilization estimates for 2007.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Development of an aggregation assay to screen FimH antagonists

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Quorum sensing is necessary for the virulence of Pseudomonas aeruginosa during urinary tract infection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Iron dictates the virulence of Pseudomonas aeruginosa in urinary tract infections.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Resistance in gram-negative bacteria: Enterobacteriaceae.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Phenotypic characters of urinary isolates of Pseudomonas aeruginosa & their association with mouse renal colonization.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Pyelonephritic Escherichia coli expressing P fimbriae decrease immune response of the mouse kidney.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Intracellular bacterial biofilm-like pods in urinary tract infections.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Cloning of aas, a gene encoding a Staphylococcus saprophyticus surface protein with adhesive and autolytic properties.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457377

Complicated urinary tract infections

28 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Strategies to prevent catheter-associated urinary tract infections in acute care hospitals: 2014 update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

The etiology of urinary tract infection: traditional and emerging pathogens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Candida Urinary Tract Infection: Pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Histological changes in the urinary bladder secondary to urethral catheterisation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Influence of drainage conditions on mucosal bladder damage by indwelling catheters. I. Pressure study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Quorum sensing and virulence of Pseudomonas aeruginosa during urinary tract infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

The outer membrane protein, antigen 43, mediates cell-to-cell interactions within Escherichia coli biofilms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Elastase LasB of Pseudomonas aeruginosa promotes biofilm formation partly through rhamnolipid-mediated regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Analysis of the hierarchy of quorum-sensing regulation in Pseudomonas aeruginosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

Serotypes, hemagglutinins, siderophore synthesis, and serum resistance of Klebsiella isolates causing human urinary tract infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3432

31 March 2020

Identifiers

DOI

10.1038/NRMICRO3432

1 reference

Dimensions Publication ID

491393

1001049530

0 references

491393

1 reference

1 reference

1 reference